SCHEMBL3682833

SCHEMBL3682833

CC(C)Oc1ccc(OC(=O)C(C)C(C)C)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.53
PARP10 Q53GL7 1/20 0.52
ALDH1A1 P00352 4/20 0.49
LMNA P02545 2/20 0.49
TP53 P04637 2/20 0.49
MEN1 O00255 1/20 0.49
GAA P10253 1/20 0.49
POLB P06746 1/20 0.49
GLA P06280 1/20 0.47
ELANE P08246 2/20 0.47
ALDH1A3 P47895 1/20 0.46
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
HTR2A P28223 1/20 0.44
MAPK1 P28482 1/20 0.41
ACACB O00763 3/20 0.40
MAPT P10636 1/20 0.40
NLRP1 Q9C000 1/20 0.40
ACACA Q13085 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3678450 0.82 ELANE (0.48) KMT2AMEN1GAAGLAELANE
SCHEMBL11991231 0.82 ELANE (0.48) PARP10ALDH1A1LMNAGAAELANE
SCHEMBL2294888 0.80 ATM (0.58) KMT2AALDH1A1LMNATP53MEN1
SCHEMBL11991232 0.79 KMT2A (0.56) KMT2APARP10ALDH1A1TP53ELANE
SCHEMBL13764948 0.79 ELANE (0.59) KMT2APARP10ALDH1A1LMNATP53
SCHEMBL3688114 0.79 XDH (0.40) KMT2APARP10ALDH1A1LMNAMEN1
SCHEMBL22425715 0.78 PTGS2 (0.46) POLBELANENPC1RAB9AHTR2A
SCHEMBL11991245 0.78 ELANE (0.44) KMT2AALDH1A1MEN1ELANERAB9A
SCHEMBL3948122 0.78 LMNA (0.59) KMT2APARP10ALDH1A1LMNATP53
SCHEMBL19441077 0.77 MGLL (0.47) KMT2APARP10ALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10584141-B2 Recyclable metathesis catalysts THE TRUSTEES OF BOSTON COLLEGE (US) 2020-03-10 US disclosed
US-20190309001-A1 RECYCLABLE METATHESIS CATALYSTS THE TRUSTEES OF BOSTON COLLEGE 2019-10-10 US disclosed
US-10336781-B2 Recyclable metathesis catalysts THE TRUSTEES OF BOSTON COLLEGE (US) 2019-07-02 US disclosed
US-20160168181-A1 RECYCLABLE METATHESIS CATALYSTS THE TRUSTEES OF BOSTON COLLEGE 2016-06-16 US disclosed
EP-1313559-B2 RECYCLABLE METATHESIS CATALYSTS TRUSTEES BOSTON COLLEGE (US) 2012-10-24 EP disclosed
US-20100292486-A1 RECYCLABLE METATHESIS CATALYSTS HOVEYDA AMIR H 2010-11-18 US disclosed
US-7723255-B2 Recyclable metathesis catalysts THE TRUSTEES OF BOSTON COLLEGE (US) 2010-05-25 US disclosed
EP-1313559-B1 RECYCLABLE METATHESIS CATALYSTS TRUSTEES BOSTON COLLEGE (US) 2009-11-11 EP disclosed
US-20050272598-A1 Recyclable metathesis catalysts THE TRUSTEES OF BOSTON COLLEGE 2005-12-08 US disclosed
US-6921735-B2 Recyclable metathesis catalysts THE TRUSTEES OF BOSTON COLLEGE (US) 2005-07-26 US disclosed
EP-1313559-A4 RECYCLABLE METATHESIS CATALYSTS TRUSTEES BOSTON COLLEGE (US) 2004-02-04 EP disclosed
EP-1313559-A2 RECYCLABLE METATHESIS CATALYSTS Trustees of Boston College (US) 2003-05-28 EP disclosed
US-20020107138-A1 Recyclable metathesis catalysts NATIONAL SCIENCE FOUNDATION 2002-08-08 US disclosed
WO-2002014376-A2 RECYCLABLE METATHESIS CATALYSTS TRUSTEES OF BOSTON COLLEGE (US) 2002-02-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190309001-A1 RECYCLABLE METATHESIS CATALYSTS DNMT1, CARM1, ZMYND8 KMT2A 792/4885PARP10 2421/4885ALDH1A1 2343/4885
US-20100292486-A1 RECYCLABLE METATHESIS CATALYSTS DNMT1, CARM1, ZMYND8 KMT2A 792/4885PARP10 2421/4885ALDH1A1 2343/4885
US-10584141-B2 Recyclable metathesis catalysts DNMT1, CARM1, ZMYND8 KMT2A 792/4885PARP10 2421/4885ALDH1A1 2343/4885
US-10336781-B2 Recyclable metathesis catalysts DNMT1, CARM1, ZMYND8 KMT2A 792/4885PARP10 2421/4885ALDH1A1 2343/4885
US-20160168181-A1 RECYCLABLE METATHESIS CATALYSTS DNMT1, CARM1, ZMYND8 KMT2A 792/4885PARP10 2421/4885ALDH1A1 2343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.