SCHEMBL3682919

SCHEMBL3682919

CC([Al])Oc1c(C(C)(C)C)cc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
RARG P13631 1/20 0.31
RXRA P19793 1/20 0.31
PPARG P37231 1/20 0.31
POLB P06746 1/20 0.30
HSP90AA1 P07900 1/20 0.30
HMGCR P04035 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1304653 0.78 GABRA1 (0.33) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL3678171 0.77 CYP1A2 (0.33) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL26876686 0.76 RARG (0.33) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL4246696 0.76 RXRA (0.30) RXRAPPARG
SCHEMBL18400749 0.74 POLB (0.38) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL3678167 0.73 CYP1A2 (0.33) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL16606238 0.73 PTGS1 (0.39) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL26875010 0.72 CYP1A2 (0.36) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL2947022 0.72 PTGS2 (0.47) GABRA1GABRB2CYP1A2CYP3A4TSHR
SCHEMBL3678169 0.71 GABRA1 (0.34) GABRA1GABRB2CYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100081770-A1 GRAFTED AND FUNCTIONALIZED HIGH 1,4-TRANS POLYBUTADIENE WITH AROMATIC ORGANOSULFUR COMPOUND KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2010-04-01 US claimed