Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689497 | 0.97 | CA1 (0.42) | CA1CA2CA7CA9ACHE | |
| Silver SCHEMBL1451626 | 0.93 | CA1 (0.40) | CA1CA2CA7CA9ACHE | |
| SCHEMBL912936 | 0.93 | CA1 (0.40) | CA1CA2CA7CA9ACHE | |
| Water SCHEMBL16539351 | 0.93 | CA1 (0.40) | CA1CA2CA7CA9ACHE | |
| SCHEMBL6430652 | 0.93 | CA1 (0.40) | CA1CA2CA7CA9ACHE | |
| SCHEMBL623289 | 0.93 | CA1 (0.40) | CA1CA2CA7CA9ACHE | |
| Lithium Ion SCHEMBL1451658 | 0.93 | CA1 (0.40) | CA1CA2CA7CA9ACHE | |
| Water SCHEMBL2688804 | 0.90 | CA1 (0.38) | CA1CA2CA7CA9ACHE | |
| Silver SCHEMBL9414258 | 0.90 | CA1 (0.38) | CA1CA2CA7CA9ACHE | |
| Water SCHEMBL17686587 | 0.90 | CA1 (0.38) | CA1CA2CA7CA9ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024196901-A2 | A HIGH THROUGHPUT ION-SENSING METHOD | WHITESIDES GEORGE M (US) | 2024-09-26 | — | — | WO | claimed |
| US-20150119848-A1 | METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2015-04-30 | — | — | US | claimed |
| EP-2856133-A1 | IMPROVED METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION | The University of Tennessee Research Foundation (US) | 2015-04-08 | — | — | EP | claimed |
| WO-2013180814-A1 | IMPROVED METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-12-05 | — | — | WO | claimed |
| EP-3629928-B1 | METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE | THE UNIV OF TENNESSEE RESEARCH FOUNDATION (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024196901-A2 | A HIGH THROUGHPUT ION-SENSING METHOD | WHITESIDES GEORGE M (US) | 2024-09-26 | — | — | WO | disclosed |
| US-11686722-B2 | Compositions and methods to detect molecules in a sample | INFUSENSE CORP. (US) | 2023-06-27 | — | — | US | disclosed |
| US-11375929-B2 | Method and device for detection of bioavailable drug concentration in a fluid sample | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2022-07-05 | — | — | US | disclosed |
| EP-3629928-A1 | METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE | The University of Tennessee Research Foundation (US) | 2020-04-08 | — | — | EP | disclosed |
| US-20190331656-A1 | COMPOSITIONS AND METHODS TO DETECT MOLECULES IN A SAMPLE | INFUSENSE CORP. | 2019-10-31 | — | — | US | disclosed |
| EP-3555609-A1 | COMPOSITIONS AND METHODS TO DETECT MOLECULES IN A SAMPLE | Infusense Corp. (US) | 2019-10-23 | — | — | EP | disclosed |
| WO-2018222820-A1 | METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2018-12-06 | — | — | WO | disclosed |
| US-20150119848-A1 | METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2015-04-30 | — | — | US | disclosed |
| EP-2856133-A1 | IMPROVED METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION | The University of Tennessee Research Foundation (US) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013180814-A1 | IMPROVED METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-12-05 | — | — | WO | disclosed |
| US-7671210-B2 | Process for production of optically active cyclopropanecarboxylate compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-02 | — | — | US | disclosed |
| EP-1783130-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2009-12-30 | — | — | EP | disclosed |
| US-20090048450-A1 | Process for production of optically active cyclopropanecarboxylate compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-1783130-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2007-05-09 | — | — | EP | disclosed |
| EP-0617277-A1 | Ion-selective electrode and process for preparing the same | HITACHI, LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048450-A1 | Process for production of optically active cyclopropanecarboxylate compound | CBR3, C9, CBR1 | CA1 659/4885CA2 199/4885CA7 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.