SCHEMBL3683324

SCHEMBL3683324

CCc1ccc2c(c1)C([Zr](Cl)Cl)c1cc(CC)ccc1-2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
MAPK1 P28482 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
TRPA1 O75762 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
PDK2 Q15119 1/20 0.32
KDM4E B2RXH2 2/20 0.31
GAA P10253 2/20 0.31
TSHR P16473 1/20 0.31
ATM Q13315 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
BRD4 O60885 1/20 0.30
HPGD P15428 1/20 0.30
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8920105 0.74 ALDH1A1 (0.42) ALDH1A1MAPK1L3MBTL1SMN1; SMN2NPC1
SCHEMBL5082800 0.74 ALDH1A1 (0.42) ALDH1A1MAPK1L3MBTL1SMN1; SMN2NPC1
Hydrochloric Acid SCHEMBL17698553 0.72 ALDH1A1 (0.41) ALDH1A1MAPK1L3MBTL1SMN1; SMN2NPC1
Hydrochloric Acid SCHEMBL3683321 0.72 ALDH1A1 (0.41) ALDH1A1MAPK1L3MBTL1SMN1; SMN2NPC1
SCHEMBL31026796 0.71 TRPA1 (0.42) ALDH1A1MAPK1L3MBTL1SMN1; SMN2NPC1
SCHEMBL2855439 0.69 ALDH1A1 (0.39) ALDH1A1L3MBTL1NPC1LMNAMAPT
SCHEMBL13437594 0.67 PDK2 (0.50) ALDH1A1MAPK1L3MBTL1SMN1; SMN2NPC1
SCHEMBL27355090 0.67 NPC1 (0.49) ALDH1A1MAPK1L3MBTL1SMN1; SMN2NPC1
SCHEMBL12017104 0.67 NPC1 (0.49) ALDH1A1MAPK1L3MBTL1SMN1; SMN2NPC1
SCHEMBL3162094 0.66 LMNA (0.38) ALDH1A1MAPK1L3MBTL1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1473323-B1 Polyethylene composition and process for producing same TOSOH CORP (JP) 2016-04-27 EP disclosed
CN-103391950-A Ethylene-alfa-olefin copolymer and molded article SUMITOMO CHEMICAL CO 2013-11-13 CN disclosed
CN-102459436-B Resin composition for crosslinking/foam molding, crosslinked molded foam, member for footwear, and footwear SUMITOMO CO LTD 2013-07-31 CN disclosed
CN-101575430-B Polyethylene resin composition and laminating body formed therefrom TOSOH CORP 2013-05-15 CN disclosed
CN-101878235-A Ethylene-alpha-olefin copolymer and molded article SUMITOMO CHEMICAL CO 2010-11-03 CN disclosed
US-7678866-B2 Polyethylene composition and process for producing same TOSOH CORPORATION (JP) 2010-03-16 US disclosed
CN-101575430-A Polyethylene resin composition and laminating body formed therefrom TOSIH CORP (JP) 2009-11-11 CN disclosed
CN-101341176-A Ethylene polymer, catalyst for producing ethylene polymer, and method for producing ethylene polymer TOSOH CORP (JP) 2009-01-07 CN disclosed
EP-1964860-A1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER Tosoh Corporation (JP) 2008-09-03 EP disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed