Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107416 | 0.98 | TSHR (0.41) | TSHRTP53PLA2G4BCES2RARB | |
| SCHEMBL28279514 | 0.92 | NAAA (0.42) | TSHRTP53PLA2G4BCES2RARB | |
| SCHEMBL580750 | 0.87 | NAAA (0.39) | TSHRTP53CES2GPR84ALDH1A1 | |
| SCHEMBL10992651 | 0.85 | AKR1B1 (0.47) | TSHRPLA2G4BPPARGPPARDPPARA | |
| SCHEMBL20856996 | 0.82 | LPAR3 (0.44) | TSHRCES2PPARGPPARDPPARA | |
| SCHEMBL12245346 | 0.82 | CES2 (0.37) | TSHRTP53PLA2G4BCES2MEN1 | |
| SCHEMBL19692733 | 0.82 | ALDH1A1 (0.41) | TSHRTP53CES2PPARGPPARD | |
| SCHEMBL107415 | 0.81 | CES2 (0.38) | CES2ALDH1A1 | |
| SCHEMBL10936529 | 0.80 | ALDH1A1 (0.40) | TSHRTP53PLA2G4BCES2GPR84 | |
| SCHEMBL30441966 | 0.80 | CES2 (0.42) | TSHRCES2PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2223959-A1 | TIRE | Bridgestone Corporation (JP) | 2010-09-01 | — | — | EP | disclosed |