SCHEMBL580750

SCHEMBL580750

CCCCCCCCCCCCCCCCCCOC(CCCCCCCCCCCCCCCC)(OO)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.39
CES2 O00748 3/20 0.39
HCAR2 Q8TDS4 1/20 0.38
EPHX1 P07099 1/20 0.37
TSHR P16473 4/20 0.36
PLA2G2A P14555 1/20 0.36
TP53 P04637 1/20 0.36
ALDH1A1 P00352 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.35
SLC22A8 Q8TCC7 1/20 0.35
GPR84 Q9NQS5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3683450 0.87 TSHR (0.42) CES2TSHRTP53ALDH1A1SLC22A6
SCHEMBL28279514 0.87 NAAA (0.42) NAAACES2HCAR2EPHX1TSHR
SCHEMBL30441966 0.87 CES2 (0.42) CES2TSHRALDH1A1SLC22A6SLC22A8
SCHEMBL107416 0.86 TSHR (0.41) CES2TSHRPLA2G2ATP53ALDH1A1
SCHEMBL20856996 0.82 LPAR3 (0.44) NAAACES2HCAR2EPHX1TSHR
SCHEMBL28082939 0.77 LPAR3 (0.40) NAAACES2HCAR2EPHX1TSHR
SCHEMBL28082463 0.77 LPAR3 (0.40) NAAACES2HCAR2EPHX1TSHR
SCHEMBL9460775 0.77 NAAA (0.42) NAAACES2HCAR2EPHX1TSHR
SCHEMBL22227808 0.76 TSHR (0.47) NAAACES2HCAR2EPHX1TSHR
SCHEMBL28393383 0.76 NAAA (0.43) NAAACES2EPHX1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 756 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023208523-A1 COMPOSITION WITH A POLYPHENOL, AN AQUEOUS DISPERSION OF WAX, A NONIONIC SURFACTANT WITH AN HLB OF GREATER THAN OR EQUAL TO 8 AND AN UNCOATED IRON OXIDE L'OREAL (FR) 2023-11-02 WO claimed
CN-113316473-B Cosmetic O/W mascara composition comprising polyurethane resin 布茨公司 2023-09-08 CN claimed
EP-3682948-B1 COSMETIC O/W MASCARA COMPOSITIONS COMPRISING POLYURETHANE RESIN BOOTS CO PLC (GB) 2023-08-30 EP claimed
EP-2863996-B1 LIQUID COSMETIC COMPOSITION COMPRISING AN OIL, HYDROPHOBIC SILICA AEROGEL PARTICLES AND A WAX WITH A MELTING POINT OF GREATER THAN 60°C OREAL (FR) 2021-03-24 EP claimed
US-20200093717-A1 EXFOLIATING AND HYDRATING MAKEUP REMOVING COMPOSITIONS L'OREAL (FR) 2020-03-26 US claimed
US-10576031-B1 Exfoliating and hydrating makeup removing compositions L'OREAL (FR) 2020-03-03 US claimed
US-10470997-B2 Liquid cosmetic composition comprising an oil, hydrophobic silica aerogel particles and a wax with a melting point of greater than 60° celsius L'OREAL (FR) 2019-11-12 US claimed
EP-1920757-B1 Cosmetic composition containing citric acid derivatives ORÉAL L (FR) 2016-05-11 EP claimed
US-20150164775-A1 LIQUID COSMETIC COMPOSITION COMPRISING AN OIL, HYDROPHOBIC SILICA AEROGEL PARTICLES AND A WAX WITH A MELTING POINT OF GREATER THAN 60 DEGREES CELSIUS L'OREAL (FR) 2015-06-18 US claimed
EP-2863996-A1 LIQUID COSMETIC COMPOSITION COMPRISING AN OIL, HYDROPHOBIC SILICA AEROGEL PARTICLES AND A WAX WITH A MELTING POINT OF GREATER THAN 60°C L'Oréal (FR) 2015-04-29 EP claimed
EP-2168562-A1 Eyelash make-up composition and packaging system L'OREAL (FR) 2010-03-31 EP claimed
EP-2168563-A2 Eyelash make-up composition and packaging system L'OREAL (FR) 2010-03-31 EP claimed
WO-2010010306-A2 COSMETIC HEAT TREATMENT METHOD USING COMPOSITION HAVING A LOW OIL CONTENT L'OREAL (FR) 2010-01-28 WO claimed
EP-1534219-B1 MAKE-UP COMPOSITION FOR KERATIN FIBRES SUCH AS EYELASHES OREAL (FR) 2009-12-16 EP claimed
WO-2009080955-A2 COSMETIC MAKE-UP AND/OR CARE METHOD USING A SILOXANE RESIN AND A POLAR WAX L'OREAL (FR) 2009-07-02 WO claimed
EP-1552806-B1 Long lasting make-up composition for keratin fibers OREAL (FR) 2008-09-10 EP claimed
EP-1870075-A1 Mascara comprising at least 21% of wax and a filler L'Oréal (FR) 2007-12-26 EP claimed
EP-1424059-B1 Cosmetic composition comprising a tacky wax OREAL (FR) 2006-06-07 EP claimed
US-20060099231-A1 Make-up composition for keratin fibres such as eyelashes L'OREAL S.A. (FR) 2006-05-11 US claimed
US-20050180936-A1 Keratin fiber make-up composition with long-term stability L'OREAL S.A. (FR) 2005-08-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10470997-B2 Liquid cosmetic composition comprising an oil, hydrophobic silica aerogel particles and a wax with a melting point of greater than 60° celsius CUTA, IL33, LSS NAAA 3123/4885CES2 543/4885HCAR2 3250/4885
US-20050180936-A1 Keratin fiber make-up composition with long-term stability KRT18, DSG1, DSP NAAA 4680/4885CES2 4681/4885HCAR2 4844/4885
US-20150164775-A1 LIQUID COSMETIC COMPOSITION COMPRISING AN OIL, HYDROPHOBIC SILICA AEROGEL PARTICLES AND A WAX WITH A MELTING POINT OF GREATER THAN 60 DEGREES CELSIUS CUTA, IL33, LIPA NAAA 3106/4885CES2 560/4885HCAR2 2643/4885
US-20200093717-A1 EXFOLIATING AND HYDRATING MAKEUP REMOVING COMPOSITIONS DSG1, AQP3, AQP1 NAAA 808/4885CES2 1668/4885HCAR2 2083/4885
US-20060099231-A1 Make-up composition for keratin fibres such as eyelashes KRT18, DSG1, CUTA NAAA 4571/4885CES2 4768/4885HCAR2 4835/4885
US-10576031-B1 Exfoliating and hydrating makeup removing compositions DSG1, AQP3, AQP1 NAAA 808/4885CES2 1668/4885HCAR2 2083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.