Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812210 | 0.83 | ALDH1A1 (0.48) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL9812193 | 0.83 | ALDH1A1 (0.48) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL173301 | 0.80 | ALDH1A1 (0.64) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL13169390 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL8235357 | 0.77 | ALDH1A1 (0.47) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| Water SCHEMBL29179560 | 0.77 | ALDH1A1 (0.61) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| Bromide SCHEMBL8645583 | 0.77 | ALDH1A1 (0.61) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| Phosphine SCHEMBL28908227 | 0.77 | ALDH1A1 (0.61) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL436340 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL14760181 | 0.77 | ALDH1A1 (0.47) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765264-B1 | DENTAL COMPOSITION CONTAINING UNSATURATED CARBOSILANE CONTAINING COMPONENTS | MINNESOTA MINING MFG GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| EP-1765264-B1 | DENTAL COMPOSITION CONTAINING UNSATURATED CARBOSILANE CONTAINING COMPONENTS | MINNESOTA MINING MFG GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| EP-1765265-B1 | DENTAL COMPOSITION CONTAINING AN EPOXY FUNCTIONAL CARBOSILANE COMPOUND | 3M ESPE AG (DE) | 2010-10-06 | — | — | EP | disclosed |
| US-7799846-B2 | Dental composition containing an epoxy functional carbosilane compound | 3M ESPE AG (DE) | 2010-09-21 | — | — | US | disclosed |
| US-7799846-B2 | Dental composition containing an epoxy functional carbosilane compound | 3M ESPE AG (DE) | 2010-09-21 | — | — | US | disclosed |
| US-7700714-B2 | Optical element and achromatic lens | TEIJIN CHEMICALS, LTD. (JP) | 2010-04-20 | — | — | US | disclosed |
| US-7662869-B2 | Curable di- or polyunsaturated carbosilane containing silicon-aryl bondand no silicon-oxygen bonds; initiator, filler, dyes, pigments, thixotropic agents, flow control agents, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavors; crowns, bridges | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-02-16 | — | — | US | disclosed |
| US-20090143560-A1 | Optical Element and Achromatic Lens | TEIJIN CHEMICALS, LTD. | 2009-06-04 | — | — | US | disclosed |
| EP-1947131-A1 | OPTICAL DEVICE AND ACHROMATIC LENS | Teijin Chemicals, Ltd. (JP) | 2008-07-23 | — | — | EP | disclosed |
| US-20080070193-A1 | Dental Composition Containing Unsaturated Carbosilane Containing Components | 3M DEUTSCHLAND GMBH (DE) | 2008-03-20 | — | — | US | disclosed |
| US-20080031830-A1 | Dental Composition Containing an Epoxy Functional Carbosilane Compound | 3M DEUTSCHLAND GMBH (DE) | 2008-02-07 | — | — | US | disclosed |
| US-20080031830-A1 | Dental Composition Containing an Epoxy Functional Carbosilane Compound | 3M DEUTSCHLAND GMBH (DE) | 2008-02-07 | — | — | US | disclosed |
| EP-1765265-A1 | DENTAL COMPOSITION CONTAINING AN EPOXY FUNCTIONAL CARBOSILANE COMPOUND | 3M Espe AG (DE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005369-A1 | DENTAL COMPOSITION CONTAINING AN EPOXY FUNCTIONAL CARBOSILANE COMPOUND | 3M ESPE AG (DE) | 2006-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080031830-A1 | Dental Composition Containing an Epoxy Functional Carbosilane Compound | EPX, TAS2R41, TAS1R1 | ALDH1A1 1405/4885CYP3A4 2522/4885SMN1; SMN2 2982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.