Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647636 | 0.99 | PNMT (0.48) | PNMTDRD2DRD4DRD3HTR6 | |
| SCHEMBL7613461 | 0.97 | PNMT (0.47) | PNMTDRD2DRD4DRD3HTR6 | |
| Hydrochloric Acid SCHEMBL5346729 | 0.96 | PNMT (0.46) | PNMTDRD2DRD4DRD3HTR6 | |
| Hydrochloric Acid SCHEMBL5357721 | 0.96 | PNMT (0.46) | PNMTDRD2DRD4DRD3HTR6 | |
| SCHEMBL8857127 | 0.91 | PNMT (0.46) | PNMTDRD2DRD4DRD3HTR6 | |
| Hydrochloric Acid SCHEMBL7609023 | 0.89 | PNMT (0.44) | PNMTDRD2DRD4DRD3HTR6 | |
| SCHEMBL7638914 | 0.86 | PNMT (0.50) | PNMTDRD2DRD4DRD3HTR6 | |
| Hydrochloric Acid SCHEMBL6558664 | 0.84 | PNMT (0.48) | PNMTDRD2DRD4DRD3HTR6 | |
| SCHEMBL8580933 | 0.76 | — | — | |
| SCHEMBL3684526 | 0.76 | HTR6 (0.36) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524624-B1 | Use of organometallic flurorenyl compounds. | PHILLIPS PETROLEUM CO (US) | 2002-05-15 | — | — | EP | claimed |
| US-6162936-A | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 2000-12-19 | — | — | US | disclosed |
| US-5571880-A | CATALYSTS FOR POLYMERIZATION OF OLEFINS ESPECIALLY TO OBTAIN SYNDIOTACTIC POLYMERS | PHILLIPS PETROLEUM COMPANY (US) | 1996-11-05 | — | — | US | disclosed |
| US-5436305-A | Preparing polymer catalysts by reaction of alkali metal alkyl and fluorenyl in solvent | PHILLIPS PETROLEUM COMPANY (US) | 1995-07-25 | — | — | US | disclosed |