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Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL3684772

CCc1cc(Cc2cc(CC)c(N)c(CC)c2Cl)c(Cl)c(CC)c1N.N.N

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 2/20 0.37
▸ POLB P06746 1/20 0.37
▸ DHFR P00374 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15262 0.98 HTT (0.38) HTTPOLBDHFRALDH1A1MAPT
SCHEMBL9361265 0.92 HTT (0.35) HTTPOLBDHFRALDH1A1MAPT
SCHEMBL9361400 0.91 POLB (0.34) HTTPOLBDHFRALDH1A1
SCHEMBL166928 0.91 POLB (0.34) HTTPOLBDHFR
SCHEMBL166178 0.89 DHFR (0.42) HTTPOLBDHFR
SCHEMBL30854914 0.88 HTT (0.37) HTTPOLBALDH1A1MAPTSMN1; SMN2
SCHEMBL9365179 0.84 POLB (0.33) HTTPOLB
SCHEMBL9361610 0.83 HTT (0.39) HTTPOLBALDH1A1MAPT
SCHEMBL9362431 0.82 ALDH1A1 (0.36) HTTPOLBDHFRALDH1A1SMN1; SMN2
SCHEMBL117142 0.80 HTT (0.46) HTTPOLBDHFRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838587-B2 Polymer materials containing dispersed carbon nanotubes ARKEMA FRANCE (FR) 2010-11-23 — — US disclosed
US-20080207817-A1 Polymer Materials Containing Dispersed Carbon Nanotubes ARKEMA FRANCE (FR) 2008-08-28 — — US disclosed