Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 9/20 | 1.00 |
| ▸ | ACHE | P22303 | 3/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | TLR3 | O15455 | 1/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KIT | P10721 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | GABRP | O00591 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986061 | 1.00 | CHUK (1.00) | CHUKACHEKDM4EMAPTMEN1 | |
| SCHEMBL31451646 | 0.89 | ACHE (1.00) | CHUKACHEKDM4EMAPTMEN1 | |
| SCHEMBL27351126 | 0.89 | ACHE (1.00) | CHUKACHEKDM4EMAPTMEN1 | |
| SCHEMBL4823690 | 0.89 | CHUK (0.79) | CHUKACHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL24277019 | 0.83 | ACHE (0.73) | CHUKACHEKDM4EMAPTMEN1 | |
| SCHEMBL2597652 | 0.82 | ALDH1A1 (1.00) | CHUKACHEKDM4EMAPTMEN1 | |
| SCHEMBL29391519 | 0.82 | ALDH1A1 (1.00) | CHUKACHEKDM4EMAPTMEN1 | |
| SCHEMBL27098859 | 0.81 | ACHE (0.79) | CHUKACHEKDM4EMAPTMEN1 | |
| SCHEMBL30667681 | 0.81 | ACHE (0.79) | CHUKACHEKDM4EMAPTMEN1 | |
| SCHEMBL31451485 | 0.80 | ALDH1A1 (0.72) | CHUKACHEKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63250378-A | — | — | None | — | — | JP | disclosed |
| US-20250367173-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | LIGACHEM BIOSCIENCES INC (KR) | 2025-12-04 | — | — | US | disclosed |
| EP-4540245-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | LigaChem Biosciences Inc. (KR) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023242631-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | LEGOCHEM BIOSCIENCES, INC. (KR) | 2023-12-21 | — | — | WO | disclosed |
| WO-2023242631-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | LEGOCHEM BIOSCIENCES, INC. (KR) | 2023-12-21 | — | — | WO | disclosed |
| EP-3538529-B1 | SELECTIVE INHIBITORS OF GENOTOXIC STRESS-INDUCED IKK/NF-KB PATHWAYS | MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN HELMHOLTZ GEMEINSCHAFT (DE) | 2022-01-19 | — | — | EP | disclosed |
| US-11028084-B2 | Selective inhibitors of gentotoxic steress-induced IKK/NF-κB pathways | MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (DE) | 2021-06-08 | — | — | US | disclosed |
| EP-3538529-A1 | SELECTIVE INHIBITORS OF GENOTOXIC STRESS-INDUCED IKK/NF-kB PATHWAYS | Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (DE) | 2019-09-18 | — | — | EP | disclosed |
| US-20190276452-A1 | SELECTIVE INHIBITORS OF GENTOTOXIC STERESS-INDUCED IKK/NF-KB PATHWAYS | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2019-09-12 | — | — | US | disclosed |
| CN-109963850-A | The selective depressant of genotoxicity stress-induced IKK/NF- kB pathway | 马克思-德布鲁克-分子医学中心亥姆霍兹联合会 | 2019-07-02 | — | — | CN | disclosed |
| US-7658957-B2 | Anti-arthritic herbal composition and method thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-02-09 | — | — | US | disclosed |
| US-7618663-B2 | Anti-arthritic herbal composition and method thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2009-11-17 | — | — | US | disclosed |
| US-20080118587-A1 | ANTI-ARTHRITIC HERBAL COMPOSITION AND METHOD THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (CSIR) (IN) | 2008-05-22 | — | — | US | disclosed |
| US-20080118588-A1 | ANTI-ARTHRITIC HERBAL COMPOSITION AND METHOD THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-05-22 | — | — | US | disclosed |
| US-7348336-B2 | Substituted β-carbolines | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-03-25 | — | — | US | disclosed |
| US-7348336-B2 | Substituted β-carbolines | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-03-25 | — | — | US | disclosed |
| US-7338674-B2 | Anti-arthritic herbal composition and method thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-03-04 | — | — | US | disclosed |
| US-20060141061-A1 | Anti-arthritic herbal composition and method thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2006-06-29 | — | — | US | disclosed |
| WO-2006061675-A1 | ANTI-ARTHRITIC HERBAL COMPOSITION AND METHOD OF PRODUCTION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2006-06-15 | — | — | WO | disclosed |
| JP-S63250378-A | INDOLE DERIVATIVE | MITSUBISHI KASEI CORP | 1988-10-18 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250367173-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | ENPP1, ENPP3, SMPD1 | CHUK 1840/4885ACHE 259/4885KDM4E 2886/4885 |
| US-11028084-B2 | Selective inhibitors of gentotoxic steress-induced IKK/NF-κB pathways | IKBKB, NFKBIA, IKBKE | CHUK 4/4885ACHE 2568/4885KDM4E 2954/4885 |
| US-20190276452-A1 | SELECTIVE INHIBITORS OF GENTOTOXIC STERESS-INDUCED IKK/NF-KB PATHWAYS | IKBKB, NFKBIA, IKBKE | CHUK 6/4885ACHE 2671/4885KDM4E 2948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.