SCHEMBL368505

SCHEMBL368505

CCCCn1c(C)c(C2(c3ccc(N(C)C)cc3C)OC(=O)c3ccccc32)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
POLB P06746 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
MAPT P10636 1/20 0.41
ALOX12 P18054 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
ALDH1A1 P00352 6/20 0.40
HPGD P15428 2/20 0.40
CYP3A4 P08684 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
HIF1A Q16665 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PGR P06401 4/20 0.39
RORA P35398 4/20 0.39
RORC P51449 4/20 0.39
RORB Q92753 4/20 0.39
KDM4E B2RXH2 1/20 0.37
CNR2 P34972 2/20 0.37
CNR1 P21554 1/20 0.37
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13871608 0.96 MAPT (0.40) LMNAPOLBNPSR1MAPTALOX12
SCHEMBL11252089 0.92 ALDH1A1 (0.39) LMNAPOLBNPSR1MAPTALOX12
SCHEMBL11248239 0.89 CNR2 (0.38) MAPTALDH1A1HPGDCYP3A4TDP1
SCHEMBL5697823 0.89 MAPT (0.39) LMNAPOLBNPSR1MAPTALOX12
SCHEMBL10657523 0.89 LMNA (0.39) LMNAPOLBNPSR1MAPTALOX12
SCHEMBL10658993 0.89 LMNA (0.41) LMNAPOLBNPSR1MAPTALOX12
SCHEMBL29460369 0.86 ALDH1A1 (0.55) LMNAPOLBMAPTALDH1A1HPGD
SCHEMBL3801882 0.86 ALDH1A1 (0.55) LMNAPOLBMAPTALDH1A1HPGD
SCHEMBL29361500 0.86 PGR (0.47) LMNAPOLBNPSR1ALDH1A1HPGD
SCHEMBL27560 0.86 PGR (0.47) LMNAPOLBNPSR1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210023867-A1 IMAGING MEDIUM HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2021-01-28 US disclosed
US-20120075401-A1 PRINT HEAD PULSING TECHNIQUES FOR MULTICOLOR PRINTERS ZINK IMAGING, INC. 2012-03-29 US disclosed
US-8098269-B2 Print head pulsing techniques for multicolor printers ZINK IMAGING, INC. (US) 2012-01-17 US disclosed
US-20110050829-A1 PRINT HEAD PULSING TECHNIQUES FOR MULTICOLOR PRINTERS ZINK IMAGING, LLC 2011-03-03 US disclosed
US-7791626-B2 Print head pulsing techniques for multicolor printers ZINK IMAGING, INC. (US) 2010-09-07 US disclosed
US-7635660-B2 multicolor thermal imaging system wherein each color can be printed alone or in selectable proportion with the other color(s) by controlling the temperature of the thermal printhead(s) and the time thermal energy is applied to the image-forming layers; adequate color separation ZINK IMAGING, INC. (US) 2009-12-22 US disclosed
US-20080238967-A1 PRINT HEAD PULSING TECHNIQUES FOR MULTICOLOR PRINTERS ZINK IMAGING, LLC 2008-10-02 US disclosed
EP-1399318-B1 THERMAL IMAGING SYSTEM ZINK IMAGING LLC (US) 2007-02-14 EP disclosed
US-7166558-B2 Thermal imaging system ZINK IMAGING, LLC (US) 2007-01-23 US disclosed
US-20060270552-A1 Thermal imaging system ZINK IMAGING, LLC 2006-11-30 US disclosed
US-6906735-B2 Thermal imaging system POLAROID CORPORATION (US) 2005-06-14 US disclosed
US-20050052521-A1 Thermal imaging system POLAROID CORPORATION 2005-03-10 US disclosed
US-6801233-B2 Thermal imaging system POLAROID CORPORATION 2004-10-05 US disclosed
US-20040180284-A1 Thermal imaging system POLAROID CORPORATION 2004-09-16 US disclosed
EP-1399318-A1 THERMAL IMAGING SYSTEM Polaroid Corporation (US) 2004-03-24 EP disclosed
US-20030125206-A1 Thermal imaging system ZINK HOLDINGS LLC 2003-07-03 US disclosed
WO-2002096665-A1 THERMAL IMAGING SYSTEM POLAROID CORPORATION (US) 2002-12-05 WO disclosed