Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.56 |
| ▸ | FABP3 | P05413 | 7/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10351200 | 1.00 | CA2 (0.72) | CA2NFKB1GPR84FABP3CYP3A4 | |
| SCHEMBL3922309 | 1.00 | CA2 (0.72) | CA2NFKB1GPR84FABP3CYP3A4 | |
| Acetic Acid SCHEMBL10613802 | 0.96 | CA2 (0.68) | CA2NFKB1GPR84FABP3CYP3A4 | |
| SCHEMBL3438387 | 0.96 | CA2 (0.72) | CA2NFKB1GPR84FABP3CYP3A4 | |
| SCHEMBL9451772 | 0.96 | CA2 (0.72) | CA2NFKB1GPR84FABP3CYP3A4 | |
| SCHEMBL16972964 | 0.96 | CA2 (0.72) | CA2NFKB1GPR84FABP3CYP3A4 | |
| Potassium Ion SCHEMBL9246555 | 0.96 | CA2 (0.72) | CA2NFKB1GPR84FABP3CYP3A4 | |
| Lithium Ion SCHEMBL5680426 | 0.96 | CA2 (0.72) | CA2NFKB1GPR84FABP3CYP3A4 | |
| SCHEMBL9577313 | 0.96 | CA2 (0.72) | CA2NFKB1GPR84FABP3CYP3A4 | |
| Lithium Ion SCHEMBL11438840 | 0.96 | CA2 (0.72) | CA2NFKB1GPR84FABP3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816433-B2 | Polyacetal resin composition and article thereof | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-10-19 | — | — | US | disclosed |
| US-20070078204-A1 | Polyacetal resin composition and article thereof | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2007-04-05 | — | — | US | disclosed |
| US-6506850-B1 | Obtained by heat treatment in presence of quaternary ammonium compound; gears, cams, automobile parts, television, videos, communications, optical disks | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2003-01-14 | — | — | US | disclosed |