Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369523 | 0.84 | BRD4 (0.46) | KDM4EALDH1A1BRD4TSHRHSD17B10 | |
| SCHEMBL30661803 | 0.74 | BRD4 (0.43) | KDM4EALDH1A1BRD4TSHRHSD17B10 | |
| SCHEMBL16057538 | 0.72 | MAPT (0.40) | KDM4EALDH1A1BRD4HSD17B10HPGD | |
| SCHEMBL23400310 | 0.70 | CYBB (0.40) | KDM4EBRD4TSHRHSD17B10RAB9A | |
| SCHEMBL10308970 | 0.68 | PKM (0.49) | KDM4EALDH1A1MAPK1MAPT | |
| SCHEMBL23399411 | 0.68 | TSHR (0.40) | KDM4EALDH1A1BRD4TSHRHSD17B10 | |
| SCHEMBL370920 | 0.67 | MYC (0.54) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL23400962 | 0.66 | CYBB (0.39) | KDM4EALDH1A1BRD4TSHRHSD17B10 | |
| SCHEMBL370726 | 0.66 | MYC (0.45) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL23402091 | 0.65 | MAPT (0.41) | KDM4EALDH1A1BRD4TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |