Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3688565 | 0.87 | L3MBTL1 (0.47) | ALDH1A1KMT2ASMN1; SMN2TDP1MAPT | |
| SCHEMBL1583220 | 0.85 | CA12 (0.47) | ALDH1A1KMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL3690725 | 0.82 | L3MBTL1 (0.57) | ALDH1A1KMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL608324 | 0.81 | HTT (0.34) | ALDH1A1KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL24011663 | 0.79 | HTT (0.46) | ALDH1A1KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL334924 | 0.79 | KDM4E (0.56) | ALDH1A1KMT2AHTTSMN1; SMN2TSHR | |
| SCHEMBL1479121 | 0.77 | KMT2A (0.40) | ALDH1A1KMT2AMEN1HTTTDP1 | |
| SCHEMBL1478723 | 0.77 | LMNA (0.50) | ALDH1A1KMT2ASMN1; SMN2TSHRTP53 | |
| SCHEMBL3686294 | 0.76 | MAPT (0.48) | ALDH1A1BRD4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1481400 | 0.76 | MAPT (0.51) | ALDH1A1KMT2AMEN1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231720-B1 | FUNCTIONALIZED POLYMER AND METHODS FOR MAKING AND USING | BRIDGESTONE CORP (JP) | 2013-08-14 | — | — | EP | disclosed |
| US-8236892-B2 | Functionalized polymer and methods for making and using | BRIDGESTONE CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100311899-A1 | FUNCTIONALIZED POLYMER AND METHODS FOR MAKING AND USING | BRIDGESTONE CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |