SCHEMBL3686474

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3692854	0.84	IFNAR1 (0.38)	IFNAR1LMNASMN1; SMN2RECQLALDH1A1
	SCHEMBL3683980	0.81	IFNAR1 (0.36)	IFNAR1LMNASMN1; SMN2RECQLALDH1A1
	SCHEMBL5341823	0.78	CTBP2 (0.39)	LMNAALDH1A1HPGDMAPT
	SCHEMBL4917129	0.73	CYP1A2 (0.42)	LMNAALDH1A1CYP2C9CYP2C19CRHBP
	SCHEMBL5340353	0.71	P2RX7 (0.46)	LMNASMN1; SMN2ALDH1A1MAPK1MAPT
	SCHEMBL3684854	0.71	LMNA (0.64)	IFNAR1LMNASMN1; SMN2RECQLALDH1A1
	SCHEMBL5343945	0.70	P2RX7 (0.36)	CYP2C9MAPT
	SCHEMBL14089600	0.68	LMNA (0.49)	IFNAR1LMNASMN1; SMN2RECQLALDH1A1
	SCHEMBL4437147	0.66	ALDH1A1 (0.46)	IFNAR1LMNAALDH1A1MAPK1CYP2C9
	SCHEMBL4438686	0.66	HPGD (0.55)	LMNASMN1; SMN2RECQLALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.