Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 3/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010023 | 0.75 | MMP2 (0.68) | FFAR1ALDH1A1HDAC1HDAC2MMP12 | |
| SCHEMBL8618654 | 0.75 | FFAR1 (1.00) | FFAR1FFAR4MMP12MMP13MMP2 | |
| SCHEMBL1211561 | 0.75 | FFAR1 (1.00) | FFAR1FFAR4MMP12MMP13MMP2 | |
| SCHEMBL5284928 | 0.74 | HDAC1 (0.53) | ALDH1A1MAPTHDAC1HDAC2CA1 | |
| SCHEMBL25360940 | 0.74 | FFAR1 (0.65) | FFAR1HDAC1HDAC2FFAR4MMP12 | |
| SCHEMBL7630944 | 0.73 | FFAR1 (0.96) | FFAR1FFAR4MMP12MMP13MMP2 | |
| Hydrochloric Acid SCHEMBL5753893 | 0.73 | FFAR1 (0.96) | FFAR1FFAR4MMP12MMP13MMP2 | |
| SCHEMBL9813754 | 0.72 | TBXA2R (0.55) | FFAR1ALDH1A1HDAC1HDAC2MMP12 | |
| SCHEMBL21465371 | 0.72 | CA1 (0.68) | CA1CA2CA12CA9CA4 | |
| SCHEMBL2872694 | 0.72 | SIGMAR1 (0.66) | MAPTHDAC1HDAC2HDAC8RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-20060217433-A1 | Sulfonamide derivatives as ppar modulators | ELI LILLY AND COMPANY (US) | 2006-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060217433-A1 | Sulfonamide derivatives as ppar modulators | PPARD, PPARA, PPARG | FFAR1 14/4885ALDH1A1 1050/4885MAPT 3428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.