Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.68 |
| ▸ | MMP7 | P09237 | 2/20 | 0.68 |
| ▸ | MMP14 | P50281 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 3/20 | 0.56 |
| ▸ | MMP1 | P03956 | 2/20 | 0.56 |
| ▸ | MMP9 | P14780 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | MMP12 | P39900 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001018 | 0.88 | HSD11B1 (0.69) | HTTNPSR1KDM4EHDAC1HDAC2 | |
| SCHEMBL7307785 | 0.88 | MMP2 (0.54) | MMP2MMP7MMP14HTTNPSR1 | |
| Hydrochloric Acid SCHEMBL10584023 | 0.86 | HSD11B1 (0.67) | HTTNPSR1KDM4EHDAC1HDAC2 | |
| SCHEMBL7010857 | 0.86 | HSD11B1 (0.58) | MMP2MMP7MMP14HTTNPSR1 | |
| SCHEMBL27466099 | 0.86 | MMP2 (0.59) | MMP2MMP7MMP14HDAC1HDAC2 | |
| SCHEMBL7014945 | 0.84 | HTT (0.55) | MMP2MMP7MMP14HTTNPSR1 | |
| SCHEMBL7077673 | 0.82 | HTT (0.50) | MMP2MMP7MMP14HTTNPSR1 | |
| SCHEMBL7075505 | 0.82 | HSD11B1 (0.62) | MMP2MMP7MMP14HTTNPSR1 | |
| SCHEMBL7862104 | 0.82 | HDAC1 (0.57) | MMP2MMP7MMP14HTTNPSR1 | |
| SCHEMBL7870815 | 0.81 | HTT (0.64) | HTTNPSR1KDM4EHSD11B1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1168709-C | Alpha-hydroxy, amino and -fluoro derivatives of beta-sulphenyl hydroxamic acids matrix metalloproteinases inhibitors | ����Լ��ҩ�﹫˾ | 2004-09-29 | — | — | CN | disclosed |
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1302462-A1 | SULFONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-04-16 | — | — | EP | disclosed |
| CN-1278247-A | Alpha-hydroxy, -amino and halo derivatives of beta-sulfonyl hydroxamic acids as matrix metalloproteinase inhibitors | PHARMACIA & UPJHN CO (US) | 2000-12-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | SULT1E1, RRS1, SHH | MMP2 4420/4885MMP7 3988/4885MMP14 4447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.