Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | SI | P14410 | 4/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL368690 | 0.85 | GPR84 (0.59) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL29885154 | 0.85 | GPR84 (0.59) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL24813005 | 0.77 | SPR (0.53) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL7234600 | 0.77 | F7 (0.58) | MAPTKMT2AMEN1GPR84HTR2A | |
| SCHEMBL30708185 | 0.77 | SPR (0.53) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL15741304 | 0.77 | MTNR1A (0.45) | MAPTKMT2AMEN1 | |
| SCHEMBL27514167 | 0.75 | GPR84 (0.61) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL2494144 | 0.73 | HTR2C (0.52) | MAPTKDM4ERECQLKMT2AALDH1A1 | |
| SCHEMBL4001528 | 0.72 | GPR84 (0.57) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL27939077 | 0.72 | GPR84 (0.53) | MGAMGAASIMGAM2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405506-A1 | Tetrapeptide type-B CCK receptor ligands | ABBOTT LABORATORIES (US) | 1991-01-02 | — | — | EP | disclosed |