Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10338925 | 0.87 | GPR174 (0.58) | SMN1; SMN2LMNANPSR1GPR174MAPT | |
| SCHEMBL6288038 | 0.81 | GPR174 (0.53) | SMN1; SMN2LMNAHPGDNPSR1GPR174 | |
| SCHEMBL5931918 | 0.81 | GPR174 (0.53) | SMN1; SMN2LMNAHPGDNPSR1GPR174 | |
| SCHEMBL8161826 | 0.79 | WDR5 (0.57) | LMNAHPGDGPR174GAAMAPT | |
| SCHEMBL8388308 | 0.79 | GPR174 (0.51) | SMN1; SMN2LMNANPSR1GPR174MAPT | |
| SCHEMBL1072731 | 0.79 | GPR174 (0.51) | LMNAHPGDNPSR1GPR174GAA | |
| SCHEMBL10645437 | 0.79 | CHRNB2 (0.39) | SMN1; SMN2LMNAHPGDNPSR1GPR174 | |
| SCHEMBL9983332 | 0.78 | GPR174 (0.50) | SMN1; SMN2LMNAGPR174GAAMAPT | |
| SCHEMBL22527417 | 0.78 | GPR174 (0.50) | GPR174CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL10912649 | 0.78 | ALDH1A1 (0.50) | SMN1; SMN2LMNAHPGDNPSR1GPR174 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754781-B2 | Active energy beam-curable composition | TOAGOSEI CO., LTD. (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20080194727-A1 | Active Energy Beam-Curable Composition | TOAGOSEI CO., LTD. (JP) | 2008-08-14 | — | — | US | disclosed |
| EP-1857469-A1 | ACTIVE ENERGY RAY-CURABLE COMPOSITION | TOAGOSEI CO., LTD. (JP) | 2007-11-21 | — | — | EP | disclosed |
| EP-0524477-A2 | Resin composition having high refractive index properties | NIPPON SHEET GLASS CO., LTD. (JP) | 1993-01-27 | — | — | EP | disclosed |
| US-5171806-A | Phenylmaleimide, dially diphenate, bisphenol ester; lenses | NIPPON SHEET GLASS CO., LTD. (JP) | 1992-12-15 | — | — | US | disclosed |
| US-4374854-A | Fungicidal sulfur-containing phenyl esters and mixtures thereof | GAF CORPORATION (US) | 1983-02-22 | — | — | US | disclosed |