Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 4/20 | 0.50 |
| ▸ | MMP3 | P08254 | 3/20 | 0.50 |
| ▸ | MMP13 | P45452 | 3/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP7 | P09237 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791357 | 1.00 | ADAMTS4 (0.61) | ADAMTS4ALDH1A1HSD17B10L3MBTL1SLC1A3 | |
| SCHEMBL1798546 | 0.86 | MMP9 (0.67) | ADAMTS4ALDH1A1HSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL1798547 | 0.86 | MMP9 (0.67) | ADAMTS4ALDH1A1HSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL790069 | 0.85 | ADAMTS4 (0.81) | ADAMTS4ALDH1A1HSD17B10L3MBTL1SLC1A3 | |
| SCHEMBL702793 | 0.85 | ADAMTS4 (0.81) | ADAMTS4ALDH1A1HSD17B10L3MBTL1SLC1A3 | |
| SCHEMBL702794 | 0.85 | ADAMTS4 (0.81) | ADAMTS4ALDH1A1HSD17B10L3MBTL1SLC1A3 | |
| SCHEMBL1903552 | 0.84 | SLC1A3 (0.56) | ADAMTS4ALDH1A1HSD17B10SLC1A3SLC1A2 | |
| SCHEMBL11578980 | 0.84 | ADAMTS4 (0.59) | ADAMTS4ALDH1A1HSD17B10L3MBTL1SLC1A3 | |
| SCHEMBL17318887 | 0.83 | ADAMTS4 (0.62) | ADAMTS4ALDH1A1HSD17B10L3MBTL1SLC1A3 | |
| SCHEMBL1906746 | 0.82 | KMT2A (0.51) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010014744-A1 | INHIBITORS OF HEPATITIS C VIRUS INFECTION | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-02-04 | — | — | WO | claimed |