Hydrochloric Acid

Hydrochloric Acid

SCHEMBL3683368

CC1=Cc2c(-c3cccc4ccccc34)cccc2C1[Hf+2](C1C(C)=Cc2c(-c3cccc4ccccc34)cccc21)[SiH](C)C.[Cl-].[Cl-]

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TDP2 O95551 1/20 0.33
HPGD P15428 1/20 0.33
ALOX12 P18054 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP3 P42574 1/20 0.33
HTT P42858 1/20 0.33
GALK1 P51570 1/20 0.33
BLM P54132 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
KDM4C Q9H3R0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3688170 0.85 PBRM1 (0.31)
Hydrochloric Acid SCHEMBL29556837 0.82 PDCD1 (0.31)
Hydrochloric Acid SCHEMBL217395 0.82 PDCD1 (0.31)
Hydrochloric Acid SCHEMBL31126407 0.82 CA12 (0.34) CA12CA1CA2CA9ALDH1A1
Hydrochloric Acid SCHEMBL7832824 0.82 CA12 (0.34) CA12CA1CA2CA9ALDH1A1
Hydrochloric Acid SCHEMBL3687203 0.78 SYK (0.33)
Hydrochloric Acid SCHEMBL28744080 0.78 ENPP3 (0.33) CA12CA1CA2CA9ALDH1A1
Hydrochloric Acid SCHEMBL1044599 0.76 HTR1A (0.32) CA12CA1CA2CA9ALDH1A1
Hydrochloric Acid SCHEMBL5854090 0.76 ENPP3 (0.32) CA12CA1CA2CA9ALDH1A1
Hydrochloric Acid SCHEMBL4060835 0.76 ALDH1A1 (0.35) CA12CA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015065784-A1 NOVEL ALUMINUM ALKYL WITH C5 CYCLIC AND PENDENT OLEFIN POLYMERIZATION CATALYST EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-05-07 WO claimed
US-20150119540-A1 Novel Aluminum Alkyl With C5 Cyclic and Pendent Olefin Polymerization Catalyst EXXONMOBIL CHEMICAL PATENTS INC. 2015-04-30 US claimed
US-7741417-B2 Preparation of polymerization catalyst activators utilizing indole-modified silica supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-06-22 US claimed
US-20070055028-A1 Preparation of polymerization catalyst activators utilizing indole-modified silica supports EXXONMOBIL CHEMICAL PATENTS INC. 2007-03-08 US claimed
CN-116199813-B Long chain branched polypropylene and preparation method thereof 中国科学院化学研究所 2025-02-11 CN disclosed
US-9321854-B2 Aluminum alkyl with C5 cyclic and pendent olefin polymerization catalyst EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-04-26 US disclosed
WO-2015065784-A1 NOVEL ALUMINUM ALKYL WITH C5 CYCLIC AND PENDENT OLEFIN POLYMERIZATION CATALYST EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-05-07 WO disclosed
US-20150119540-A1 Novel Aluminum Alkyl With C5 Cyclic and Pendent Olefin Polymerization Catalyst EXXONMOBIL CHEMICAL PATENTS INC. 2015-04-30 US disclosed
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US disclosed
WO-2004106394-A1 COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-12-09 WO disclosed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US disclosed
US-6613845-B1 Propylene/ethylene-α-olefin block copolymer and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-09-02 US disclosed
US-5990242-A Propylene/ethylene-α-olefin block copolymer and process for processing the same SUMITOMO CHEMICAL CO., LTD. (JP) 1999-11-23 US disclosed