SCHEMBL3687267

SCHEMBL3687267

Fc1cc(C(F)(F)F)c(F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.34
KDM1A O60341 1/20 0.31
CES2 O00748 1/20 0.31
GLA P06280 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.31
GPR3 P46089 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30741240 1.00 KIF11 (0.34) KIF11KDM1ACES2GLAPOLB
Tetrafluoroethylene SCHEMBL8463376 0.91 KIF11 (0.34) KIF11CES2
SCHEMBL25791363 0.84 KIF11 (0.32) KIF11
SCHEMBL4215888 0.83
Piperidine SCHEMBL6382431 0.82 ALDH1A1 (0.33)
SCHEMBL24743369 0.79 KIF11 (0.32) KIF11
SCHEMBL8702494 0.79 CES2 (0.32) CES2
SCHEMBL5139030 0.79
SCHEMBL3257911 0.79
SCHEMBL465082 0.77 KIF11 (0.34) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117239231-A Electrolyte additive for lithium battery, electrolyte and preparation method of electrolyte 哈尔滨工业大学 2023-12-15 CN claimed
US-6114590-A Process for the preparation of polyhalogenated benzotrifluorides, benzotrichlorides and benzoyl chlorides and new trihalogenobenzotrichlorides and -benzoyl chlorides BAYER AKTIENGESELLSCHAFT (DE) 2000-09-05 US claimed
EP-0781747-B1 Process for the preparation of 2,3,4,5-tetrafluoro-benzotrifluoride BAYER AG (DE) 1999-09-01 EP claimed
EP-0781747-A1 Process for the preparation of 2,3,4,5-tetrafluoro-benzotrifluoride BAYER AG (DE) 1997-07-02 EP claimed
EP-0607824-A2 Method for the production of multiply halogenated benzotrifluorides, benzotrichlorides and benzoyl chlorides as well as trihalobenzotrichlorides and -benzoyl chlorides BAYER AG (DE) 1994-07-27 EP claimed
JP-8231446-A None JP disclosed
JP-6279357-A None JP disclosed
US-12559454-B2 Benzenesulfonamide derivatives and uses thereof 2692372 ONTARIO, INC. (CA) 2026-02-24 US disclosed
CN-118160076-B Etching gas and etching method using the same 大金工业株式会社 2024-08-27 CN disclosed
CN-118160076-A Etching gas and etching method using the same 大金工业株式会社 2024-06-07 CN disclosed
US-20240092756-A1 METHODS AND COMPOSITION FOR KRAS MODIFICATIONS DUNAD THERAPEUTICS LTD. (GB) 2024-03-21 US disclosed
US-20240018153-A1 BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF 2692372 ONTARIO, INC. (CA) 2024-01-18 US disclosed
EP-0453842-A2 Fluor subsituted derivatives of alpha-(5-aryloxy-naphthalen-1-yloxy)propionic acid BAYER AG (DE) 1991-10-30 EP disclosed
US-5030252-A Polytarylene ethers; permselectivity THE DOW CHEMICAL COMPANY (US) 1991-07-09 US disclosed
EP-0416365-A2 Carbocyclic anilide derivatives BAYER AG (DE) 1991-03-13 EP disclosed
EP-0416359-A1 Carbocyclic anilide carbamates BAYER AG (DE) 1991-03-13 EP disclosed
EP-0339418-A2 Substituted anilides of the cycloalkyl- or heterocyclyl-carboxylic acids BAYER AG (DE) 1989-11-02 EP disclosed
US-4868347-A SOLVENT EXTRACTION BAYER AKTIENGESELLSCHAFT (DE) 1989-09-19 US disclosed
EP-0270964-A2 Process for obtaining substituted fluorobenzenes BAYER AG (DE) 1988-06-15 EP disclosed
US-4038276-A PROCESS FOR THE PRODUCTION OF FINELY DIVIDED SOLID CYANURIC CHLORIDE DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1977-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240092756-A1 METHODS AND COMPOSITION FOR KRAS MODIFICATIONS KRAS, NRAS, HRAS KIF11 2167/4885KDM1A 3061/4885CES2 4841/4885
US-12559454-B2 Benzenesulfonamide derivatives and uses thereof NR2E1, NR2C2, NR3C1 KIF11 4365/4885KDM1A 4598/4885CES2 2247/4885
US-20240018153-A1 BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF ABCG2, ABCB1, ARSA KIF11 3174/4885KDM1A 3006/4885CES2 396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.