SCHEMBL3689102

SCHEMBL3689102

C=Cc1cc(F)c(O)c(C(F)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
APP P05067 1/20 0.35
KIF11 P52732 2/20 0.34
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22882569 0.88 APP (0.39) HTR2AHTR2CHTR2BAPPKIF11
SCHEMBL3214111 0.81 ERN1 (0.37) PTGS1PTGS2
SCHEMBL26793682 0.79 PTGS1 (0.39) HTR2AHTR2CHTR2BAPPPTGS1
SCHEMBL26348258 0.77 TRPA1 (0.35) PTGS1
SCHEMBL15616078 0.74 TDP1 (0.37) HTR2AHTR2CHTR2BKIF11
SCHEMBL29190121 0.73 XDH (0.45)
SCHEMBL28047962 0.73 ERN1 (0.43) KIF11
SCHEMBL816358 0.73 HTR2A (0.36) HTR2AHTR2CHTR2BAPP
SCHEMBL25140015 0.72 PTGS1 (0.47) PTGS1PTGS2
SCHEMBL11855670 0.72 KIF11 (0.53) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1720063-B1 Resin containing ketene-aldehyde copolymer NIPPON SODA CO (JP) 2010-04-07 EP disclosed
EP-1482361-B1 ACID-DEGRADABLE RESIN COMPOSITIONS CONTAINING KETENE-ALDEHYDE COPOLYMER NIPPON SODA CO (JP) 2007-10-03 EP disclosed
EP-1720063-A1 Resin containing ketene-aldehyde copolymer NIPPON SODA CO., LTD. (JP) 2006-11-08 EP disclosed
US-7105272-B2 Acid-degradable resin compositions containing ketene-aldehyde copolymer NIPPON SODA CO., LTD. (JP) 2006-09-12 US disclosed
US-20050130057-A1 Acid-degradable resin compositions containing ketene-aldehyde copolymer NIPPON SODA CO., LTD. (JP) 2005-06-16 US disclosed
EP-1482361-A1 ACID-DEGRADABLE RESIN COMPOSITIONS CONTAINING KETENE-ALDEHYDE COPOLYMER NIPPON SODA CO., LTD. (JP) 2004-12-01 EP disclosed