SCHEMBL3689259

SCHEMBL3689259

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nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL221966 0.90 KDM4E (0.35) LMNA
SCHEMBL5613152 0.83 TSHR (0.38)
SCHEMBL9157486 0.82 LPAR5 (0.36)
E968 SCHEMBL1679761 0.80 PDE4A (0.31)
SCHEMBL26131305 0.79 THRA (0.35)
SCHEMBL28506569 0.77 PTGS1 (0.33)
Glycidol SCHEMBL20261856 0.77 ALDH1A1 (0.33)
SCHEMBL2889653 0.76
SCHEMBL27345298 0.75
SCHEMBL221551 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3728339-B1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS AMO Ireland (IE) 2022-07-06 EP claimed
EP-3502147-A1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS Merck Patent GmbH (DE) 2019-06-26 EP claimed
US-20240216228-A1 CALCIUM AND FLUORINE IONS RELEASING DENTAL COMPOSITION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-07-04 US disclosed
US-20240189196-A1 INITIATOR SYSTEM WITH POLYMERIZABLE THIOUREA COMPONENT, DENTAL COMPOSITION AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-06-13 US disclosed
EP-4257570-A1 COMPOUNDS BASED ON RECYCLED COMPOUNDS FOR MULTICOMPONENT REACTIVE RESIN SYSTEMS FOR CHEMICAL FIXATION Hilti Aktiengesellschaft (LI) 2023-10-11 EP disclosed
EP-4177235-A1 PULVERIZED RECYCLED MATERIALS AS FILLERS FOR MULTICOMPONENT SYSTEMS FOR CHEMICAL FIXATION HILTI Aktiengesellschaft (LI) 2023-05-10 EP disclosed
EP-3728339-B1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS AMO Ireland (IE) 2022-07-06 EP disclosed
EP-3728339-A1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS Merck Patent GmbH (DE) 2020-10-28 EP disclosed
EP-3502147-A1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS Merck Patent GmbH (DE) 2019-06-26 EP disclosed
EP-2236122-B1 Polymer-modified glass ionomer cement VOCO GMBH (DE) 2017-08-30 EP disclosed
EP-2236122-A2 Polymer-modified glass ionomer cement VOCO GmbH (DE) 2010-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216228-A1 CALCIUM AND FLUORINE IONS RELEASING DENTAL COMPOSITION ORAI1, CA3, CHERP LMNA 2023/4885POLB 1239/4885MAPT 2511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.