Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687148 | 0.83 | NPY5R (0.47) | KDM4ENPY5RPOLBMAPK1KMT2A | |
| SCHEMBL3697550 | 0.83 | KDM4E (0.44) | KDM4EPOLBMAPK1KMT2AMEN1 | |
| SCHEMBL14514796 | 0.78 | HTR6 (0.49) | KDM4ENPY5RPOLBALDH1A1 | |
| SCHEMBL3686840 | 0.77 | KMT2A (0.41) | KDM4EKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL5650842 | 0.73 | NPY5R (0.45) | KDM4ENPY5RPOLBKMT2AMEN1 | |
| SCHEMBL13145817 | 0.73 | ALDH1A1 (0.47) | KDM4ENPY5RPOLBKMT2AMEN1 | |
| SCHEMBL5651335 | 0.72 | ALKBH5 (0.48) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL5651328 | 0.71 | ALKBH5 (0.48) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL5316579 | 0.71 | NPY5R (0.47) | KDM4ENPY5RPOLBKMT2AMEN1 | |
| SCHEMBL5650800 | 0.71 | ALKBH5 (0.47) | KDM4EALDH1A1HPGDFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239260-A1 | Novel compounds with antibacterial activity | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2010-10-13 | — | — | EP | disclosed |
| EP-1551829-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004035569-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2004-04-29 | — | — | WO | disclosed |