Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | UBE2M | P61081 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653634 | 0.79 | KMT2A (0.43) | KMT2AMEN1TSHRALDH1A1KDM4E | |
| SCHEMBL13145848 | 0.78 | KEAP1 (0.41) | KMT2AMEN1LMNAALDH1A1ALKBH5 | |
| SCHEMBL3689303 | 0.77 | KDM4E (0.49) | KMT2AMEN1ALDH1A1KDM4EFAAH | |
| SCHEMBL5651392 | 0.77 | SMN1; SMN2 (0.39) | KMT2AMEN1ALDH1A1KDM4EALKBH5 | |
| SCHEMBL3697550 | 0.74 | KDM4E (0.44) | KMT2AMEN1TSHRLMNAALDH1A1 | |
| SCHEMBL3693644 | 0.72 | CHRNB2 (0.31) | — | |
| SCHEMBL6216801 | 0.71 | KMT2A (0.41) | KMT2AMEN1TSHRLMNAALDH1A1 | |
| SCHEMBL3684865 | 0.70 | — | — | |
| SCHEMBL9120468 | 0.69 | KDM4E (0.56) | KMT2AMEN1TSHRALDH1A1KDM4E | |
| SCHEMBL5651335 | 0.69 | ALKBH5 (0.48) | KMT2AMEN1TSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239260-A1 | Novel compounds with antibacterial activity | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2010-10-13 | — | — | EP | disclosed |