SCHEMBL3689588

SCHEMBL3689588

CCCC[Si](NC(C)N)(OC)OC

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.32
SLC15A1 P46059 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8740863 0.88
SCHEMBL4210615 0.83 OPRM1 (0.30) OPRM1
SCHEMBL4214134 0.80
SCHEMBL2704353 0.73 LMNA (0.33)
SCHEMBL4209307 0.70 TSHR (0.35)
Isopropylamine SCHEMBL28749140 0.70 LMNA (0.48) OPRM1
SCHEMBL4208483 0.70
SCHEMBL9762625 0.69
SCHEMBL10486319 0.68 LMNA (0.31)
SCHEMBL9123795 0.68 OPRM1 (0.36) OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9388314-B2 Surface modified silicon dioxide particles EVONIK HANSE GMBH (DE) 2016-07-12 US claimed
US-20130091965-A1 METHOD FOR PRODUCING A DEPOSIT OF A MATERIAL WHICH IS LOCALIZED AND HAS A DEFINED SHAPE, ON THE SURFACE OF A SUBSTRATE COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2013-04-18 US disclosed
EP-2396360-A1 FIBER REINFORCED POLYMERIC COMPOSITES AND METHODS OF MAKING THE SAME PPG Industries Ohio, Inc. (US) 2011-12-21 EP disclosed
WO-2010093759-A1 FIBER REINFORCED POLYMERIC COMPOSITES AND METHODS OF MAKING THE SAME PPG INDUSTRIES OHIO, INC. (US) 2010-08-19 WO disclosed
US-7230060-B2 Removable coating compositions ROHM AND HAAS COMPANY (US) 2007-06-12 US disclosed
US-20070098915-A1 Method of applying removable coating compositions KOHR ALAN W 2007-05-03 US disclosed
EP-1431355-B1 COATING COMPOSITIONS HAVING A PLURALITY OF TRIGGERED RESPONSES ROHM & HAAS (US) 2006-03-22 EP disclosed
US-6855403-B2 Applying to a substrate, a first-coating composition that is removable, followed by application of a second-coating composition that is highly durable but not readily removable. ROHN AND HAAS COMPANY (US) 2005-02-15 US disclosed
US-20040138327-A1 Compositions having a plurality of triggered responses KOHR ALAN WAYNE (US) 2004-07-15 US disclosed
US-20040138328-A1 Multistage polymer emulsion; radiation curable; strippable ROHM AND HAAS COMPANY 2004-07-15 US disclosed
EP-1431324-A2 Removable coating compositions ROHM AND HAAS COMPANY (US) 2004-06-23 EP disclosed
US-20030224195-A1 Multi-layer coating composition and method of preparation ROHM AND HAAS COMPANY 2003-12-04 US disclosed