SCHEMBL4209307

SCHEMBL4209307

CCCCN[Si](CCCC)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ACHE P22303 8/20 0.34
EPHX1 P07099 3/20 0.34
LMNA P02545 1/20 0.31
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH7 P40394 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA14 Q9ULX7 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MMP2 P08253 1/20 0.30
TLR8 Q9NR97 1/20 0.30
TLR7 Q9NYK1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4199314 0.91 TSHR (0.35) TSHRACHEEPHX1LMNAADH1B
SCHEMBL28939069 0.86 LMNA (0.42) TSHREPHX1LMNAALDH1A1
SCHEMBL4540807 0.83 TSHR (0.36) TSHRACHEEPHX1ADH1BADH1C
Hydrochloric Acid SCHEMBL6898632 0.83 EPHX1 (0.38) TSHREPHX1LMNAADH1BADH1C
SCHEMBL4219137 0.82 ACHE (0.32) TSHRACHEEPHX1
SCHEMBL4213093 0.80 ACHE (0.35) TSHRACHE
SCHEMBL2704353 0.80 LMNA (0.33) TSHREPHX1LMNA
Hydrochloric Acid SCHEMBL8861283 0.78 DNM1 (0.45) TSHREPHX1ALDH1A1
SCHEMBL3916803 0.74 LMNA (0.31) LMNA
SCHEMBL10486319 0.74 LMNA (0.31) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090253873-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME TOHO CATALYST CO., LTD (JP) 2009-10-08 US disclosed
EP-1829898-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME Toho Catalyst Co., Ltd. (JP) 2007-09-05 EP disclosed