Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3689696 | 0.71 | MAOA (0.38) | MAOAMAOBGAANPSR1 | |
| SCHEMBL62756 | 0.67 | MAOA (0.46) | MAOAMAOBGAANPSR1RAB9A | |
| SCHEMBL9031787 | 0.65 | MAOA (0.50) | MAOAMAOBGAANPSR1RAB9A | |
| Xanthene SCHEMBL29378346 | 0.64 | MAOA (1.00) | MAOAMAOBGAANPSR1RAB9A | |
| SCHEMBL971330 | 0.64 | MAOA (0.70) | MAOAMAOBGAANPSR1RAB9A | |
| SCHEMBL30360775 | 0.64 | MAOA (0.70) | MAOAMAOBGAANPSR1RAB9A | |
| Xanthene SCHEMBL4267 | 0.64 | MAOA (1.00) | MAOAMAOBGAANPSR1RAB9A | |
| Xanthene SCHEMBL30586075 | 0.64 | MAOA (1.00) | MAOAMAOBGAANPSR1RAB9A | |
| Xanthene SCHEMBL9339684 | 0.64 | MAOA (1.00) | MAOAMAOBGAANPSR1RAB9A | |
| SCHEMBL2851479 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806563-A | B-N-containing organic electroluminescent material and application thereof in electroluminescent device | 广东阿格蕾雅光电材料有限公司 | 2023-03-17 | — | — | CN | claimed |
| CN-115521326-A | Organic electroluminescent material containing B-N condensed ring and application thereof | 广东阿格蕾雅光电材料有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-115368244-A | Synthetic method of 2-aryl-2- (4-aminophenyl) propane | 北京鼎材科技有限公司 | 2022-11-22 | — | — | CN | claimed |
| CN-115304623-A | Pyrimido-cyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-115260245-A | Iridium metal complex, application thereof and organic electroluminescent device | 清华大学 | 2022-11-01 | — | — | CN | claimed |
| CN-114920746-A | BTK (BTK inhibitory or degrading agent) and application thereof in medicine | 四川海思科制药有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-114805303-A | Molecule with double functions of degrading EGFR (epidermal growth factor receptor), composition and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-114605419-A | Pyrrolidine compound with anti-new coronavirus activity and application thereof in medicines | 威科检测集团有限公司 | 2022-06-10 | — | — | CN | claimed |
| CN-114539180-A | Isoxazoline-containing bisamide compound and preparation method and application thereof | 贵州大学 | 2022-05-27 | — | — | CN | claimed |
| CN-114507235-A | Compound capable of degrading BTK kinase, preparation method and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-05-17 | — | — | CN | claimed |
| WO-2007064732-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS AND MICROBIAL DISEASES | SCHERING CORPORATION (US) | 2007-06-07 | — | — | WO | claimed |
| US-20070129378-A1 | Compounds for the treatment of inflammatory disorders and microbial diseases | SCHERING CORPORATION | 2007-06-07 | — | — | US | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| US-7101873-B2 | Pyrimidinedione derivatives | BEXEL PHARMACEUTICALS INC. (US) | 2006-09-05 | — | — | US | claimed |
| US-20060194799-A1 | Novel pyrimidinedione derivatives | BEXEL PHARMACEUTICALS INC. (US) | 2006-08-31 | — | — | US | claimed |
| US-20040009975-A1 | Novel pyrimidinedione derivatives | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2004-01-15 | — | — | US | claimed |
| US-20030232813-A1 | Novel amino substituted pyrimidinone derivatives | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2003-12-18 | — | — | US | claimed |
| WO-2003084935-A2 | DIARYL PYRIMIDINONE DERIVATIVES USEFUL FOR THE TREATMENT OF INFLAMMATION AND IMMUNOGOLICAL DISEASES | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2003-10-16 | — | — | WO | claimed |
| WO-2003084936-A2 | AMINO SUBSTITUTED PYRIMIDINONE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION AND IMMUNOLOGICAL | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2003-10-16 | — | — | WO | claimed |
| WO-2003084937-A2 | PYRIMIDINEDIONE DERIVATIVES USEFUL FOR THE TREATMENT OF INFLAMMATION AND IMMUNOLOGICAL DISEASES | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2003-10-16 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232813-A1 | Novel amino substituted pyrimidinone derivatives | TPMT, TYMP, CYP3A5 | MAOA 1712/4885MAOB 952/4885GAA 1958/4885 |
| US-20040009975-A1 | Novel pyrimidinedione derivatives | TYMS, DPYD, TYMP | MAOA 3328/4885MAOB 2315/4885GAA 2902/4885 |
| US-20070129378-A1 | Compounds for the treatment of inflammatory disorders and microbial diseases | MMP12, PCSK9, ALPI | MAOA 1277/4885MAOB 1191/4885GAA 42/4885 |
| US-20060194799-A1 | Novel pyrimidinedione derivatives | TYMS, TYMP, DPYD | MAOA 3116/4885MAOB 2030/4885GAA 2900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.