Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.31 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1194391 | 0.99 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAMAPTALDH1A1HTT | |
| SCHEMBL6598296 | 0.92 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAMAPTALDH1A1HTT | |
| Bromide SCHEMBL5441123 | 0.92 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNAMAPTALDH1A1HTT | |
| SCHEMBL6596219 | 0.83 | MAPT (0.35) | SMN1; SMN2LMNAMAPTALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL1193715 | 0.82 | MAPT (0.34) | SMN1; SMN2LMNAMAPTALDH1A1HTT | |
| SCHEMBL6596459 | 0.81 | KMT2A (0.45) | SMN1; SMN2LMNAMAPTALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL1193919 | 0.80 | KMT2A (0.44) | LMNAMAPTALDH1A1HTTKMT2A | |
| SCHEMBL6597394 | 0.80 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL6618821 | 0.77 | MAPT (0.36) | SMN1; SMN2LMNAMAPTALDH1A1HTT | |
| Bromide SCHEMBL6598138 | 0.77 | MAPT (0.32) | SMN1; SMN2MAPTALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2659933-A1 | Pharmaceutical combinations comprising specified age breaker and further drugs, i.a. antihypertensive drugs, antidiabetic drugs etc. | Torrent Pharmaceuticals Ltd. (IN) | 2013-11-06 | — | — | EP | claimed |
| EP-2254563-A2 | PHARMACEUTICAL COMBINATIONS COMPRISING SPECIFIED AGE BREAKER AND FURTHER DRUGS, I.A. ANTIHYPERTENSIVE DRUGS, ANTIDIABETIC DRUGS ETC | Torrent Pharmaceuticals Ltd. (IN) | 2010-12-01 | — | — | EP | claimed |
| WO-2009093264-A2 | PHARMACEUTICAL COMBINATIONS | TORRENT PHARMACEUTICALS LTD. (IN) | 2009-07-30 | — | — | WO | claimed |