Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1193715 | 0.99 | MAPT (0.34) | MAPTALDH1A1KMT2AMEN1USP2 | |
| SCHEMBL6596459 | 0.85 | KMT2A (0.45) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL1193919 | 0.85 | KMT2A (0.44) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL3689760 | 0.83 | SMN1; SMN2 (0.39) | MAPTALDH1A1KMT2AMEN1POLB | |
| Bromide SCHEMBL1194391 | 0.82 | SMN1; SMN2 (0.38) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL6595709 | 0.81 | ALDH1A1 (0.38) | MAPTALDH1A1KMT2AMEN1USP2 | |
| SCHEMBL6598073 | 0.80 | ALDH1A1 (0.38) | MAPTALDH1A1KMT2AMEN1USP2 | |
| Hydrochloric Acid SCHEMBL1194041 | 0.80 | ALDH1A1 (0.38) | MAPTALDH1A1KMT2AMEN1USP2 | |
| SCHEMBL6595239 | 0.80 | SMYD3 (0.35) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| Bromide SCHEMBL5359685 | 0.79 | SMYD3 (0.35) | MAPTALDH1A1KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373263-B1 | HETEROCYCLIC COMPOUNDS FOR AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS | TORRENT PHARMACEUTICALS LTD (IN) | 2004-10-27 | — | — | EP | claimed |