Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1193919 | 0.99 | KMT2A (0.44) | KMT2APABPC1ATMLMNAALDH1A1 | |
| SCHEMBL6596219 | 0.85 | MAPT (0.35) | KMT2ALMNAALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL1193715 | 0.85 | MAPT (0.34) | KMT2ALMNAALDH1A1KDM4EMAPT | |
| SCHEMBL6595239 | 0.83 | SMYD3 (0.35) | KMT2ALMNAALDH1A1MAPTRAB9A | |
| Bromide SCHEMBL5359685 | 0.82 | SMYD3 (0.35) | KMT2ALMNAALDH1A1MAPTRAB9A | |
| SCHEMBL3689760 | 0.81 | SMN1; SMN2 (0.39) | KMT2ALMNAALDH1A1MAPTRAB9A | |
| Bromide SCHEMBL1194391 | 0.80 | SMN1; SMN2 (0.38) | KMT2ALMNAALDH1A1MAPTRAB9A | |
| Bromide SCHEMBL6597846 | 0.80 | KMT2A (0.46) | KMT2APABPC1ATMLMNAALDH1A1 | |
| SCHEMBL6596014 | 0.79 | KMT2A (0.47) | KMT2APABPC1ATMLMNAALDH1A1 | |
| Bromide SCHEMBL1193597 | 0.78 | KMT2A (0.49) | KMT2APABPC1ATMLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373263-B1 | HETEROCYCLIC COMPOUNDS FOR AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS | TORRENT PHARMACEUTICALS LTD (IN) | 2004-10-27 | — | — | EP | claimed |