Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5441123 | 0.99 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1LMNAHTTCASP3 | |
| SCHEMBL3689760 | 0.92 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1LMNAHTTMAPT | |
| Bromide SCHEMBL1194391 | 0.92 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1LMNAHTTMAPT | |
| SCHEMBL6597394 | 0.79 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| Bromide SCHEMBL6598138 | 0.79 | MAPT (0.32) | SMN1; SMN2ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL6618821 | 0.76 | MAPT (0.36) | SMN1; SMN2ALDH1A1LMNAHTTMAPT | |
| Bromide SCHEMBL1194586 | 0.75 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1LMNAHTTMAPT | |
| SCHEMBL6596219 | 0.75 | MAPT (0.35) | SMN1; SMN2ALDH1A1LMNAHTTMAPT | |
| Hydrochloric Acid SCHEMBL1193715 | 0.74 | MAPT (0.34) | SMN1; SMN2ALDH1A1LMNAHTTMAPT | |
| SCHEMBL6596459 | 0.73 | KMT2A (0.45) | SMN1; SMN2ALDH1A1LMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373263-B1 | HETEROCYCLIC COMPOUNDS FOR AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS | TORRENT PHARMACEUTICALS LTD (IN) | 2004-10-27 | — | — | EP | claimed |