Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | RARA | P10276 | 3/20 | 0.51 |
| ▸ | RARB | P10826 | 3/20 | 0.51 |
| ▸ | RARG | P13631 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.51 |
| ▸ | GOT1 | P17174 | 1/20 | 0.51 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641031 | 0.83 | RARB (0.67) | KMT2ARARARARBRARGLMNA | |
| SCHEMBL10014917 | 0.82 | RARA (0.52) | KMT2ARARARARBRARGLMNA | |
| SCHEMBL8426196 | 0.81 | RARA (0.54) | KMT2ARARARARBRARGLMNA | |
| SCHEMBL3690279 | 0.81 | KMT2A (0.51) | KMT2ARARARARBRARGLMNA | |
| SCHEMBL29535143 | 0.81 | RARA (0.51) | KMT2ARARARARBRARGLMNA | |
| SCHEMBL8520331 | 0.81 | RARA (0.51) | KMT2ARARARARBRARGLMNA | |
| SCHEMBL8424855 | 0.81 | RARA (0.54) | KMT2ARARARARBRARGLMNA | |
| SCHEMBL3690283 | 0.81 | KMT2A (0.51) | KMT2ARARARARBRARGLMNA | |
| SCHEMBL4748049 | 0.81 | KMT2A (0.51) | KMT2ARARARARBRARGLMNA | |
| SCHEMBL178217 | 0.81 | RARA (0.51) | KMT2ARARARARBRARGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100010265-A1 | PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | COMELY ALEXANDER CHRISTIAN | 2010-01-14 | — | — | US | disclosed |
| WO-2008126104-A2 | NOVEL PROCESS FOR PREPARATION OF ADAPALENE | INDOCO REMEDIES LIMITED (IN) | 2008-10-23 | — | — | WO | disclosed |
| WO-2007028104-A2 | NOVEL THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER, METABOLIC DISEASES AND SKIN DISORDERS | AUSPEX PHARMACEUTICALS, INC. (US) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010265-A1 | PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | AMD1, CYP51A1, DDC | KMT2A 4095/4885RARA 757/4885RARB 1157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.