SCHEMBL3690367

SCHEMBL3690367

Nc1cc(N)cc(NC=O)c1

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.32
DDX3X O00571 1/20 0.31
CYP19A1 P11511 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13723242 0.84 CYP3A4 (0.48) ALDH1A1LMNA
SCHEMBL14146533 0.81 ALDH1A1 (0.34) ALDH1A1
SCHEMBL1588979 0.80 ALDH1A1 (0.55) ALDH1A1LMNA
SCHEMBL21337861 0.80 HTR6 (0.50) ALDH1A1CYP19A1
SCHEMBL13723816 0.80 P2RX1 (0.40) ALDH1A1LMNA
SCHEMBL515010 0.77 ALDH1A1 (0.54) ALDH1A1LMNADDX3X
SCHEMBL13724304 0.75 ATAD2 (0.46) ALDH1A1LMNA
SCHEMBL5847116 0.75 ALDH1A1 (0.37) ALDH1A1
SCHEMBL28286273 0.75 ALDH1A1 (0.39) ALDH1A1LMNA
SCHEMBL424461 0.74 ALDH1A1 (0.44) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014174316-A1 METHOD OF SYNTHESISING ADCS USING AFFINITY RESINS ADC BIOTECHNOLOGY LTD (GB) 2014-10-30 WO disclosed
CN-103124590-A Thin film composite membranes incorporating carbon nanotubes GEN ELECTRIC 2013-05-29 CN disclosed
WO-2010069854-A2 MODIFIED POLYOLEFIN WAXES BASF SE (DE) 2010-06-24 WO disclosed
CN-1376545-A Manufacturing method for membrane material and multi-layer membrane material NIPPON PAINT CO LTD (JP) 2002-10-30 CN disclosed