Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28371518 | 0.86 | FOLH1 (0.59) | FOLH1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL370894 | 0.85 | RARB (0.46) | FOLH1NR1H4NPC1TSHRRAB9A | |
| SCHEMBL26365859 | 0.81 | FOLH1 (0.62) | FOLH1NR1H4NPC1TSHRRAB9A | |
| SCHEMBL2995452 | 0.81 | NR1H4 (0.74) | FOLH1NR1H4NPC1TSHRRAB9A | |
| SCHEMBL11208106 | 0.81 | TAAR1 (0.48) | FOLH1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL22442327 | 0.78 | FOLH1 (0.62) | FOLH1NR1H4PTGER1PTGER4PTGER3 | |
| SCHEMBL8368461 | 0.77 | FOLH1 (0.61) | FOLH1NR1H4PTGER1PTGER4PTGER3 | |
| SCHEMBL369421 | 0.77 | MYC (0.49) | FOLH1FABP3FABP4FABP5LMNA | |
| SCHEMBL3201162 | 0.76 | NR1H4 (0.59) | FOLH1NR1H4PTGER1KMOAKR1C3 | |
| SCHEMBL30259065 | 0.75 | KMO (0.73) | FOLH1NR1H4TSHRPTGER1KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |