Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.74 |
| ▸ | KMO | O15229 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 2/20 | 0.50 |
| ▸ | RXRB | P28702 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.49 |
| ▸ | DDT | P30046 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3201162 | 0.88 | NR1H4 (0.59) | NR1H4KMOAKR1C3AKR1C2FFAR1 | |
| SCHEMBL27959627 | 0.88 | NR1H4 (0.59) | NR1H4KMOAKR1C3AKR1C2MCL1 | |
| SCHEMBL28452076 | 0.88 | NR1H4 (0.59) | NR1H4AKR1C3AKR1C2MCL1FFAR1 | |
| Benzoic Acid SCHEMBL27717757 | 0.87 | NR1H4 (0.57) | NR1H4KMOMCL1FFAR1RXRA | |
| SCHEMBL30259065 | 0.87 | KMO (0.73) | NR1H4KMOPTGER1RXRARXRB | |
| SCHEMBL2213546 | 0.87 | KMO (0.73) | NR1H4KMOPTGER1RXRARXRB | |
| SCHEMBL23581248 | 0.86 | NR1H4 (0.58) | NR1H4KMOAKR1C3AKR1C2PTGER1 | |
| Hydrochloric Acid SCHEMBL3852306 | 0.86 | NR1H4 (0.58) | NR1H4KMOAKR1C3AKR1C2FFAR1 | |
| SCHEMBL6252539 | 0.86 | AKR1C3 (0.68) | NR1H4KMOAKR1C3AKR1C2RXRA | |
| SCHEMBL28719966 | 0.85 | NR1H4 (0.56) | NR1H4KMOAKR1C3AKR1C2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070088001-A1 | Silinane compounds as cysteine protease inhibitors | QUEST DIAGNOSTICS INVESTMENTS LLC | 2007-04-19 | — | — | US | claimed |
| US-10287230-B2 | Selective aerobic oxidation of dimethylbiphenyls | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2019-05-14 | — | — | US | disclosed |
| US-10081593-B2 | Alkyl aromatic hydroalkylation for the production of plasticizers | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2018-09-25 | — | — | US | disclosed |
| US-20180179141-A1 | SELECTIVE AEROBIC OXIDATION OF DIMETHYLBIPHENYLS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2018-06-28 | — | — | US | disclosed |
| US-20180022689-A1 | Alkyl Aromatic Hydroalkylation For The Production of Plasticizers | EXXONMOBIL CHEMICAL PATENTS INC | 2018-01-25 | — | — | US | disclosed |
| US-9815767-B2 | Alkyl aromatic hydroalkylation for the production of plasticizers | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-9534104-B2 | Plasticizer blends and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-01-03 | — | — | US | disclosed |
| EP-1306131-B1 | Cross-coupling process using a catalyst comprising a cyclic nitrogen ligand | SUMITOMO CHEMICAL CO (JP) | 2016-12-07 | — | — | EP | disclosed |
| US-20160237022-A1 | Alkyl Aromatic Hydroalkylation for the Production of Plasticizers | EXXONMOBIL CHEMICAL PATENTS INC. | 2016-08-18 | — | — | US | disclosed |
| US-9321898-B2 | Alkyl aromatic hydroalkylation for the production of plasticizers | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2016-04-26 | — | — | US | disclosed |
| EP-0520404-A1 | Transparent recording medium | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1992-12-30 | — | — | EP | disclosed |
| EP-0063374-B1 | SUBSTITUTED BIPHENYL COMPOUNDS | FMC Corporation (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4402973-A | Insecticidal (1,1'-biphenyl)-3-ylmethyl esters | FMC CORPORATION (US) | 1983-09-06 | — | — | US | disclosed |
| EP-0063374-A1 | Substituted biphenyl compounds | FMC Corporation (US) | 1982-10-27 | — | — | EP | disclosed |
| US-4329518-A | INSECTICIDES, ACARICIDES, MITICIDES | FMC CORPORATION (US) | 1982-05-11 | — | — | US | disclosed |
| EP-0049977-A1 | Insecticidal (1,1'-biphenyl)-3-ylmethyl esters, their production and use and compositions containing them | FMC Corporation (US) | 1982-04-21 | — | — | EP | disclosed |
| EP-0020685-A4 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS. | FMC CORP (US) | 1981-07-16 | — | — | EP | disclosed |
| EP-0020685-A1 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS. | FMC CORP (US) | 1981-01-07 | — | — | EP | disclosed |
| US-4214004-A | MITICIDES | FMC CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| WO-1980001163-A1 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED(1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS | FMC CORP (US) | 1980-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179141-A1 | SELECTIVE AEROBIC OXIDATION OF DIMETHYLBIPHENYLS | CYP1B1, MSMO1, CYP1A1 | NR1H4 2379/4885KMO 84/4885AKR1C3 454/4885 |
| US-20180022689-A1 | Alkyl Aromatic Hydroalkylation For The Production of Plasticizers | ALKBH3, AHR, ADH1A | NR1H4 1169/4885KMO 505/4885AKR1C3 19/4885 |
| US-10287230-B2 | Selective aerobic oxidation of dimethylbiphenyls | CYP1B1, MSMO1, CYP1A1 | NR1H4 2379/4885KMO 84/4885AKR1C3 454/4885 |
| US-10081593-B2 | Alkyl aromatic hydroalkylation for the production of plasticizers | ALKBH3, AHR, ADH1A | NR1H4 1169/4885KMO 505/4885AKR1C3 19/4885 |
| US-20160237022-A1 | Alkyl Aromatic Hydroalkylation for the Production of Plasticizers | ALKBH3, AHR, ADH1A | NR1H4 1169/4885KMO 505/4885AKR1C3 19/4885 |
| US-20070088001-A1 | Silinane compounds as cysteine protease inhibitors | CTSV, CTSB, CTSS | NR1H4 2863/4885KMO 1212/4885AKR1C3 1571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.