SCHEMBL3695498

SCHEMBL3695498

[O]Nc1ccccc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29687961 0.78
SCHEMBL157908 0.78
SCHEMBL8663534 0.77 LMNA (0.53)
SCHEMBL31482338 0.77 LMNA (0.53)
SCHEMBL31498989 0.77 TSHR (0.60)
SCHEMBL1686517 0.77 TSHR (0.60)
SCHEMBL1272337 0.75 KMT2A (0.70)
SCHEMBL11556917 0.74
SCHEMBL9311985 0.74 KMT2A (0.75)
SCHEMBL8556893 0.73 KMT2A (0.77)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9447201-B2 Polymerization inhibitor composition and method of inhibiting polymerization of distillable monomers DOW GLOBAL TECHNOLOGIES LLC (US) 2016-09-20 US disclosed
EP-2398832-B1 POLYMERIZATION INHIBITOR COMPOSITION AND METHOD OF INHIBITING POLYMERIZATION OF DISTILLABLE MONOMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-03-26 EP disclosed
EP-2398832-A1 POLYMERIZATION INHIBITOR COMPOSITION AND METHOD OF INHIBITING POLYMERIZATION OF DISTILLABLE MONOMERS Dow Global Technologies LLC (US) 2011-12-28 EP disclosed
US-20110290635-A1 POLYMERIZATION INHIBITOR COMPOSITION AND METHOD OF INHIBITING POLYMERIZATION OF DISTILLABLE MONOMERS CARNEGIE MELLON UNIVERSITY 2011-12-01 US disclosed
WO-2010096512-A1 POLYMERIZATION INHIBITOR COMPOSITION AND METHOD OF INHIBITING POLYMERIZATION OF DISTILLABLE MONOMERS DOW GLOBAL TECHNOLOGIES INC. (US) 2010-08-26 WO disclosed
US-5495045-A REACTING ALKOXYALKANOL WITH STABLE FREE RADICAL NITROXIDE IN PRESENCE OF CERIUM SALT, NITRITE COMPOUND, POLAR SOLVENT, OXIDANT AND WATER SHELL OIL COMPANY (US) 1996-02-27 US disclosed
US-5352824-A Oxidation of alkoxyalkanol using stable free radical nitroxide, copper or iron salt and nitrite catalysts in solvent SHELL OIL COMPANY (US) 1994-10-04 US disclosed
US-5336811-A Reacting corresponding aryl methanol with a free radical nitroxide in the presence of a nitrogen oxide generating compound SHELL OIL COMPANY (US) 1994-08-09 US disclosed