Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369941 | 0.85 | KMT2A (0.49) | LMNAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL1390205 | 0.84 | L3MBTL1 (0.59) | LMNAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL2397228 | 0.81 | L3MBTL1 (0.69) | LMNAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL28727176 | 0.77 | KMT2A (0.58) | LMNAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL28036009 | 0.77 | L3MBTL1 (0.63) | LMNAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL371358 | 0.76 | GAA (0.46) | LMNAMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL28169381 | 0.76 | MAPT (0.70) | LMNAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL370421 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL27704467 | 0.76 | FFAR1 (0.55) | LMNAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL370259 | 0.75 | KMT2A (0.40) | LMNAMAPTALDH1A1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |