Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 2/20 | 0.45 |
| ▸ | SI | P14410 | 2/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369644 | 0.85 | LMNA (0.55) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL1390278 | 0.82 | MGAM (0.52) | KMT2APOLBMEN1GAANPC1 | |
| SCHEMBL371358 | 0.80 | GAA (0.46) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL370421 | 0.79 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL370259 | 0.79 | KMT2A (0.40) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL17387460 | 0.78 | KMT2A (0.42) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL27895847 | 0.78 | MGAM (0.62) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL1390427 | 0.77 | GPBAR1 (0.41) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL1395270 | 0.77 | KMT2A (0.39) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL28727241 | 0.77 | ALDH1A1 (0.49) | KMT2APOLBMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |