Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458745 | 0.78 | APLNR (0.36) | ALDH1A1TP53ALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL350563 | 0.73 | ALDH1A1 (0.33) | ALDH1A1TP53ALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL9640365 | 0.70 | — | — | |
| SCHEMBL15977354 | 0.69 | CA4 (0.32) | — | |
| SCHEMBL11103839 | 0.67 | ALDH1A1 (0.30) | ALDH1A1TP53ALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL19301931 | 0.65 | HTT (0.35) | ALDH1A1TP53TSHRCYP2C19 | |
| SCHEMBL4888774 | 0.64 | APLNR (0.41) | TP53MAPK1SMN1; SMN2TDP1CYP2C19 | |
| SCHEMBL5953448 | 0.64 | ALDH1A1 (0.48) | ALDH1A1TP53ALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL221717 | 0.64 | APLNR (0.41) | TP53MAPK1SMN1; SMN2TDP1CYP2C19 | |
| Methane SCHEMBL3337389 | 0.62 | APLNR (0.39) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456254-B1 | SUPPORTED TITANIUM-CONTAINING CATALYST FOR HOMO-, CO-, AND TER-POLYMERIZATION OF OLEFINS | POLIMERI EUROPA SPA (IT) | 2010-03-24 | — | — | EP | disclosed |
| US-7449528-B2 | Supported catalyst containing active titanium in the homo, co-, and ter-polymerization of olefin-unsaturated compounds | POLIMERI EUROPA S.P.A. (IT) | 2008-11-11 | — | — | US | disclosed |
| EP-1381616-B1 | TITANIUM CATALYSTS, PREPARATION AND USE IN CO-AND TER-POLYMERIZATION OF ALPHA-OLEFINS | POLIMERI EUROPA SPA (IT) | 2007-11-28 | — | — | EP | disclosed |
| US-20060014631-A1 | Supported catalyst containing active titanium in the homo, co-, and ter-polymerization of olefin-unsaturated compounds | POLIMERI EUROPA S.P.A. (IT) | 2006-01-19 | — | — | US | disclosed |
| US-6900155-B2 | Titanium catalysts, preparation and use in co- and ter-polymerization of alpha-olefins | POLIMER EUROPA S.P.A. (IT) | 2005-05-31 | — | — | US | disclosed |
| EP-1456254-A2 | SUPPORTED TITANIUM-CONTAINING CATALYST FOR HOMO-, CO-, AND TER-POLYMERIZATION OF OLEFINS | Polimeri Europa S.p.A. (IT) | 2004-09-15 | — | — | EP | disclosed |
| US-20040143127-A1 | Titanium catalysts, preparation and use in co- and ter-polymerization of alpha-olefins | POLIMERI EUROPA S.P.A. (IT) | 2004-07-22 | — | — | US | disclosed |
| WO-2003054034-A2 | SUPPORTED TITANIUM-CONTAINING FOR HOMO-, CO-, AND TER-POLYMERIZATION OF OLEFINS | POLIMERI EUROPA S.P.A. (IT) | 2003-07-03 | — | — | WO | disclosed |
| EP-1002800-B1 | Catalysts based on vanadium, their preparation and use in the (co)polymerization of alpha-olefins. | POLIMERI EUROPA SPA (IT) | 2003-03-19 | — | — | EP | disclosed |
| US-6495641-B1 | VANADIUM COMPLEXED WITH CARBOXYLIC ACID, CHLORINE OR BROMINE AND AN ELECTRON DONOR; POLYMERS SUCH AS ETHYLENE-PROPYLENE COPOLYMER WITH LOWER RESIDUAL CHLORINE | ENICHEM S.P.A. (IT) | 2002-12-17 | — | — | US | disclosed |
| CN-1254720-A | Vanadium catalysts, their preparation and their use in the (co) polymerization of alpha-olefins | ENICHEM SPA (IT) | 2000-05-31 | — | — | CN | disclosed |
| EP-1002800-A1 | Catalysts based on vanadium, their preparation and use in the (co)polymerization of alpha-olefins. | Enichem S.p.A. (IT) | 2000-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040143127-A1 | Titanium catalysts, preparation and use in co- and ter-polymerization of alpha-olefins | AOC3, AOC2, ACACA | ALDH1A1 123/4885TP53 2252/4885ALOX15 140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.