Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786628 | 0.91 | HPRT1 (0.47) | CYP2A6ALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL3703634 | 0.91 | HPRT1 (0.47) | CYP2A6ALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL3146455 | 0.85 | HSD17B10 (0.59) | CYP2A6ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL3699078 | 0.84 | MEN1 (0.46) | ALDH1A1CYP1A2MEN1KMT2ACYP2C19 | |
| Hydrochloric Acid SCHEMBL11726958 | 0.83 | KMT2A (0.57) | CYP2A6ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL3706346 | 0.83 | MEN1 (0.44) | ALDH1A1CYP1A2MEN1KMT2ACYP2C19 | |
| SCHEMBL3778102 | 0.83 | MEN1 (0.44) | ALDH1A1CYP1A2MEN1KMT2ACYP2C19 | |
| SCHEMBL6609007 | 0.81 | ALDH1A1 (0.54) | CYP2A6ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL31304979 | 0.79 | WDR5 (0.53) | ALDH1A1CYP1A2MEN1KMT2ACYP2C19 | |
| SCHEMBL5817920 | 0.79 | ABCG2 (0.57) | ALDH1A1CYP1A2MEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460789-B1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2017-04-19 | — | — | EP | disclosed |
| US-9079830-B2 | Method for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-07-14 | — | — | US | disclosed |
| EP-2460789-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2012-06-06 | — | — | EP | disclosed |
| US-20120123154-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-17 | — | — | US | disclosed |
| EP-0039795-B1 | PROCESS FOR THE PREPARATION OF 1,2-BENZISOTHIAZOLES | BASF Aktiengesellschaft (DE) | 1983-10-12 | — | — | EP | disclosed |
| EP-0039795-A1 | Process for the preparation of 1,2-benzisothiazoles | BASF Aktiengesellschaft (DE) | 1981-11-18 | — | — | EP | disclosed |
| US-4277477-A | TREATING CARDIAC ARRHYTHMIA | BASF AKTIENGESELLSCHAFT (DE) | 1981-07-07 | — | — | US | disclosed |
| EP-0000750-A1 | 1,2-Benzisothiazoles and process for their preparation | BASF Aktiengesellschaft (DE) | 1979-02-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123154-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | AKR7A2, AOC2, CBR1 | CYP2A6 47/4885ALDH1A1 35/4885CYP1A2 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.