Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10383345 | 0.88 | CYP3A4 (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| Bromide SCHEMBL10383607 | 0.88 | CYP3A4 (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| Bromide SCHEMBL10383605 | 0.87 | CYSLTR2 (0.46) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| Bromide SCHEMBL10383355 | 0.86 | CYSLTR2 (0.46) | MAPTLTA4HCYSLTR2CYSLTR1PPARG | |
| Bromide SCHEMBL8904102 | 0.82 | PPARG (0.40) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| Bromide SCHEMBL3593928 | 0.82 | CYP1A2 (0.47) | CYP3A4MAPTSLC6A3LTA4HPPARG | |
| Hydrochloric Acid SCHEMBL10008405 | 0.80 | L3MBTL1 (0.38) | TLR8MEN1NR1I2LMNACHRM2 | |
| Hydrochloric Acid SCHEMBL28183067 | 0.79 | SIGMAR1 (0.44) | TLR8MEN1NR1I2LMNACHRM2 | |
| Bromide SCHEMBL10383978 | 0.78 | LTA4H (0.36) | MEN1LMNACYP3A4MAPTKMT2A | |
| Bromide SCHEMBL4171091 | 0.77 | SLC6A2 (0.47) | MEN1CYP3A4MAPTSLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1449887-B1 | ORGANIC SEMICONDUCTOR MATERIAL AND ORGANIC SEMICONDUCTOR ELEMENT EMPLOYING THE SAME | TORAY INDUSTRIES (JP) | 2010-11-24 | — | — | EP | disclosed |
| US-7282742-B2 | Organic thin film transistor devices and organic photovoltaic devices | TORAY INDUSTRIES, INC. (JP) | 2007-10-16 | — | — | US | disclosed |
| US-20040241900-A1 | Organic semiconductor material and organic semiconductor element employing the same | TORAY INDUSTRIES, INC. (JP) | 2004-12-02 | — | — | US | disclosed |
| EP-1449887-A1 | ORGANIC SEMICONDUCTOR MATERIAL AND ORGANIC SEMICONDUCTOR ELEMENT EMPLOYING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2004-08-25 | — | — | EP | disclosed |