Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.66 |
| ▸ | PGR | P06401 | 4/20 | 0.66 |
| ▸ | AR | P10275 | 4/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.66 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18402585 | 1.00 | CYP3A4 (0.66) | CYP3A4PGRARCHRM1ALDH1A1 | |
| SCHEMBL13981881 | 1.00 | CYP3A4 (0.66) | CYP3A4PGRARCHRM1ALDH1A1 | |
| SCHEMBL29882740 | 1.00 | CYP3A4 (0.66) | CYP3A4PGRARCHRM1ALDH1A1 | |
| SCHEMBL12826308 | 0.88 | CYP3A4 (0.65) | CYP3A4PGRARCHRM1ALDH1A1 | |
| SCHEMBL21281538 | 0.88 | CYP3A4 (0.65) | CYP3A4PGRARCHRM1ALDH1A1 | |
| SCHEMBL11426283 | 0.86 | SERPINA6 (0.60) | CYP3A4PGRARCHRM1ALDH1A1 | |
| SCHEMBL1635637 | 0.86 | ALDH1A1 (0.65) | CYP3A4PGRARCHRM1ALDH1A1 | |
| Medrogestone SCHEMBL13724822 | 0.85 | PGR (0.72) | CYP3A4PGRARCHRM1ALDH1A1 | |
| SCHEMBL666683 | 0.82 | CYP3A4 (0.58) | CYP3A4PGRARCHRM1ALDH1A1 | |
| SCHEMBL1635633 | 0.81 | CYP19A1 (0.48) | CYP3A4PGRARCHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841778-B1 | METHOD FOR PREPARING MEDROGESTONE | ABBOTT PRODUCTS GMBH (DE) | 2012-03-14 | — | — | EP | disclosed |