SCHEMBL3698006

SCHEMBL3698006

Cc1cc(C)cc(-c2ccc3ccc4ccc(-c5cc(C)cc(C)c5)cc4c3c2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
CYP1A2 P05177 5/20 0.38
CYP2A6 P11509 4/20 0.38
DYRK1A Q13627 2/20 0.35
CDK9 P50750 1/20 0.35
DYRK2 Q92630 1/20 0.35
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
CNR2 P34972 1/20 0.34
ALDH1A1 P00352 3/20 0.33
HSD17B10 Q99714 2/20 0.33
MAP4K4 O95819 1/20 0.33
HPGD P15428 1/20 0.33
ACHE P22303 1/20 0.33
TSHR P16473 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP1B1 Q16678 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032372 0.79 ENPP3 (0.34) RXRARXRBDYRK1ACDK9DYRK2
SCHEMBL839035 0.76 CYP2A6 (0.56) CYP1A2CYP2A6HSD17B1HSD17B2ESR1
SCHEMBL30687932 0.75 KIF11 (0.43) RXRARXRBALDH1A1HSD17B10HPGD
SCHEMBL28057941 0.75 KIF11 (0.43) RXRARXRBALDH1A1HSD17B10HPGD
SCHEMBL2531545 0.74 ALDH1A1 (0.53) RXRARXRBCNR2ALDH1A1ACHE
SCHEMBL4357165 0.73 ABL1 (0.67) CYP1A2HSD17B1HSD17B2ESR1ESR2
SCHEMBL1046627 0.73 RXRA (0.56) RXRARXRBCYP1A2CYP2A6CNR2
SCHEMBL18987225 0.72 ALDH1A1 (0.46) RXRARXRBCNR2ALDH1A1ACHE
SCHEMBL26550749 0.72 NPC1 (0.50) RXRARXRBDYRK1ACDK9MAP4K4
Water SCHEMBL28158610 0.71 ALDH1A1 (0.50) RXRARXRBCNR2ALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741240-B2 Transition metal compounds for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-06-22 US claimed
EP-1753773-A1 TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION ExxonMobil Chemical Patents Inc. (US) 2007-02-21 EP claimed
WO-2005118605-A1 TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2005-12-15 WO claimed