Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.42 |
| ▸ | CTSA | P10619 | 5/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP12 | P39900 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.31 |
| ▸ | PRKX | P51817 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.31 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1389775 | 0.79 | GPBAR1 (0.49) | GPBAR1CTSASLC6A9HPGDMEN1 | |
| SCHEMBL369130 | 0.79 | GPBAR1 (0.49) | GPBAR1CTSASLC6A9HPGDMEN1 | |
| SCHEMBL1389778 | 0.79 | GPBAR1 (0.49) | GPBAR1CTSASLC6A9HPGDMEN1 | |
| SCHEMBL361732 | 0.75 | GPBAR1 (0.43) | GPBAR1CTSASLC6A9MMP2MMP9 | |
| SCHEMBL370694 | 0.74 | GPBAR1 (0.37) | GPBAR1SLC6A9MEN1CYP1A2CYP2C9 | |
| SCHEMBL370503 | 0.73 | GPBAR1 (0.46) | GPBAR1MEN1CYP1A2KMT2ATDP1 | |
| SCHEMBL369976 | 0.73 | GPBAR1 (0.35) | GPBAR1 | |
| SCHEMBL370196 | 0.71 | GPBAR1 (0.42) | GPBAR1 | |
| SCHEMBL1389798 | 0.71 | GPBAR1 (0.48) | GPBAR1CTSASLC6A9HPGDMEN1 | |
| SCHEMBL1390072 | 0.71 | GPBAR1 (0.48) | GPBAR1CTSASLC6A9HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |