Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14672816 | 0.84 | CYP3A4 (0.33) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL14672817 | 0.84 | CYP3A4 (0.33) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL14672818 | 0.84 | CYP3A4 (0.33) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL2961545 | 0.82 | SIGMAR1 (0.39) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL27838302 | 0.78 | SOAT2 (0.39) | HTR2ACYP2D6 | |
| SCHEMBL11414403 | 0.72 | SIGMAR1 (0.38) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL7627841 | 0.72 | HTR6 (0.46) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL2951329 | 0.72 | HTR2A (0.38) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL1028711 | 0.70 | HTR6 (0.47) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL6675368 | 0.70 | HTR2A (0.35) | HTR2AKDM4ELMNATP53CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741417-B2 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-06-22 | — | — | US | claimed |
| US-20070055028-A1 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-03-08 | — | — | US | claimed |
| EP-2064248-B1 | PREPARATION OF POLYMERIZATION CATALYST ACTIVATORS UTILIZING INDOLE-MODIFIED SILICA SUPPORTS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2018-10-10 | — | — | EP | disclosed |
| US-7741417-B2 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-06-22 | — | — | US | disclosed |
| EP-2064248-A1 | PREPARATION OF POLYMERIZATION CATALYST ACTIVATORS UTILIZING INDOLE-MODIFIED SILICA SUPPORTS | ExxonMobil Chemical Patents Inc. (US) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008027116-A1 | PREPARATION OF POLYMERIZATION CATALYST ACTIVATORS UTILIZING INDOLE-MODIFIED SILICA SUPPORTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-03-06 | — | — | WO | disclosed |
| US-20070055028-A1 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-03-08 | — | — | US | disclosed |