SCHEMBL6675368

SCHEMBL6675368

CCCCC(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.35
KDM4E B2RXH2 2/20 0.35
LMNA P02545 2/20 0.35
TP53 P04637 1/20 0.35
CHRM2 P08172 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CHRM1 P11229 1/20 0.35
DRD2 P14416 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
NFKB1 P19838 1/20 0.35
CHRM3 P20309 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
THPO P40225 1/20 0.35
OPRK1 P41145 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8676548 0.97 KDM4E (0.36) HTR2AKDM4ELMNATP53CHRM2
Hydrochloric Acid SCHEMBL8676551 0.97 KDM4E (0.33) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL6675767 0.95 HTR2A (0.37) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL6673086 0.90 HTR2A (0.36) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL28792374 0.84 HTR2A (0.36) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL6055177 0.84 PNKP (0.34) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL1921591 0.82 HTR2A (0.38) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL9860034 0.81 HTR2A (0.37) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL9315857 0.78 LTA4H (0.33) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL30084524 0.78 SIGMAR1 (0.36) HTR2AKDM4ELMNATP53CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0963990-B1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL CO (JP) 2004-10-06 EP disclosed
US-6197990-B1 REACTING CYCLOPENTADIENE AND METAL HYDRIDE IN PRESENCE OF AMINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-03-06 US disclosed
EP-0963990-A1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-15 EP disclosed