SCHEMBL3701656

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14199648	0.90	ALDH1A1 (0.53)	ALDH1A1MAPTKDM4EL3MBTL1HPGD
	SCHEMBL3692265	0.88	MAPT (0.57)	ALDH1A1MAPTKDM4ENNMTHPGD
	SCHEMBL3693461	0.84	NNMT (0.50)	ALDH1A1MAPTKDM4ENNMTOPRM1
	SCHEMBL6228569	0.84	ALDH1A1 (0.57)	ALDH1A1MAPTKDM4EL3MBTL1HPGD
	SCHEMBL3694929	0.82	NNMT (0.47)	ALDH1A1MAPTKDM4EL3MBTL1NNMT
	SCHEMBL3689296	0.82	NNMT (0.47)	NNMTOPRM1OPRD1OPRK1
	SCHEMBL3690711	0.81	MAPK1 (0.54)	ALDH1A1MAPTKDM4ENNMTMAPK1
	SCHEMBL27569260	0.79	OPRM1 (0.43)	ALDH1A1L3MBTL1NNMTOPRM1OPRD1
	SCHEMBL3690785	0.78	ALDH1A1 (0.53)	ALDH1A1MAPTKDM4EL3MBTL1HPGD
	SCHEMBL3695000	0.78	OPRM1 (0.54)	KDM4EL3MBTL1NNMTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.