Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 13/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 12/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3702437 | 0.92 | MDM2 (0.33) | SLC16A3SLC16A1 | |
| SCHEMBL3690717 | 0.90 | ALDH1A1 (0.33) | MAPT | |
| SCHEMBL3697752 | 0.88 | ALDH1A1 (0.32) | — | |
| SCHEMBL3029606 | 0.88 | SLC16A3 (0.38) | SLC16A3SLC16A1MEN1KMT2APDE4B | |
| SCHEMBL4128944 | 0.86 | SLC16A3 (0.38) | SLC16A3SLC16A1MEN1MAPTKMT2A | |
| SCHEMBL3692824 | 0.86 | SLC16A3 (0.36) | SLC16A3SLC16A1MAPTPDE4BHTR2C | |
| SCHEMBL3700575 | 0.84 | SLC16A3 (0.40) | SLC16A3SLC16A1PDE4BHTR2CSLC6A4 | |
| SCHEMBL3706681 | 0.84 | — | — | |
| SCHEMBL3700854 | 0.82 | NAMPT (0.30) | — | |
| SCHEMBL3698141 | 0.82 | SLC16A3 (0.37) | SLC16A3SLC16A1MEN1KMT2APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009041705-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | WO | disclosed |